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    FAM86B3P family with sequence similarity 86 member B3, pseudogene [ Homo sapiens (human) ]

    Gene ID: 286042, updated on 22-Oct-2024

    Summary

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    Official Symbol
    FAM86B3Pprovided by HGNC
    Official Full Name
    family with sequence similarity 86 member B3, pseudogeneprovided by HGNC
    Primary source
    HGNC:HGNC:44371
    See related
    Ensembl:ENSG00000291049 AllianceGenome:HGNC:44371
    Gene type
    pseudo
    RefSeq status
    PROVISIONAL
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See FAM86B3P in Genome Data Viewer
    Location:
    8p23.1
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (8228570..8244865)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (11498768..11515065, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (8086092..8102387)

    Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 85 member B Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr8:7985495-7986158 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr8:7986822-7987484 Neighboring gene small nuclear ribonucleoprotein polypeptide C pseudogene 17 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:7998075-7998630 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:7998631-7999184 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr8:8024368-8025196 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:8025197-8026026 Neighboring gene ectonucleotide pyrophosphatase/phosphodiesterase 7 pseudogene 1 Neighboring gene H3K27ac hESC enhancer GRCh37_chr8:8032372-8033096 Neighboring gene ReSE screen-validated silencer GRCh37_chr8:8038385-8038619 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr8:8039463-8040118 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:8040119-8040774 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:8051667-8052173 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:8052174-8052679 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18891 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26962 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18892 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:8090135-8091040 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:8093271-8093782 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:8094341-8094892 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:8094893-8095443 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26963 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr8:8101423-8102622 Neighboring gene ALG1 like 13, pseudogene Neighboring gene Sharpr-MPRA regulatory region 6714 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26964 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26965 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18893 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:8145864-8146364 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr8:8153089-8154288 Neighboring gene uncharacterized LOC124901879 Neighboring gene PEAK1 related, kinase-activating pseudokinase 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26966 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr8:8219633-8220832 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18894 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:8233601-8234540 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:8238570-8239092 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:8239093-8239613 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18895 Neighboring gene uncharacterized LOC105379222 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr8:8256091-8256704

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Identification of FN1BP1 as a novel cell cycle regulator through modulating G1 checkpoint in human hepatocarcinoma Hep3B cells. Liu M, et al. PLoS One, 2013. PMID 23469028, Free PMC Article
    2. The sequence of the human genome. Venter JC, et al. Science, 2001 Feb 16. PMID 11181995
    3. Toward an understanding of the protein interaction network of the human liver. Wang J, et al. Mol Syst Biol, 2011 Oct 11. PMID 21988832, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. FN1BP1 might inhibit cell growth and/or colony conformation through G1 phase arrest of the Hep3B cell cycle
      Title: Identification of FN1BP1 as a novel cell cycle regulator through modulating G1 checkpoint in human hepatocarcinoma Hep3B cells.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Other Names

    • family with sequence similarity 86, member A pseudogene

    Clone Names

    • FLJ10661, FLJ60033

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_024361.1 RNA Sequence

      Status: PROVISIONAL

      Description
      Transcript Variant: This variant (2) contains an alternate segment in the 3' region, as compared to variant 1.
      Source sequence(s)
      AC068020
      Related
      ENST00000522601.5

    2. NR_024362.1 RNA Sequence

      Status: PROVISIONAL

      Description
      Transcript Variant: This variant (1) represents the longer transcript.
      Source sequence(s)
      AC068020
      Related
      ENST00000834666.1

    3. NR_024363.1 RNA Sequence

      Status: PROVISIONAL

      Description
      Transcript Variant: This variant (3) lacks internal exons and has an alternate exon at the 3' terminus, as compared to variant 1.
      Source sequence(s)
      AC068020
      Related
      ENST00000588728.5

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

      Range
      8228570..8244865
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 PATCHES

    Genomic

    1. NW_018654717.1 Reference GRCh38.p14 PATCHES

      Range
      5103000..5119295 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060932.1 Alternate T2T-CHM13v2.0

      Range
      11498768..11515065 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials