T01D1.4 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase homolog;putative inactive acireductone dioxygenase 1 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: T01D1.4
Official Full Name: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase homolog;putative inactive acireductone dioxygenase 1
Primary source: WormBase:WBGene00020149
Locus tag: CELE_T01D1.4
See related: AllianceGenome:WB:WBGene00020149
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable acireductone dioxygenase [iron(II)-requiring] activity. Predicted to be involved in methionine metabolic process. Predicted to be located in cytoplasm and nucleus. Orthologous to human ADI1 (acireductone dioxygenase 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See T01D1.4 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 3

Sequence:: Chromosome: II; NC_003280.10 (176997..179093, complement)

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003280.10

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Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

T01D1.4 (e-PCR)
- UniSTS:319596

T01D1.1 (e-PCR)
- UniSTS:318390

STS2-225 (e-PCR)
- UniSTS:241901

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables acireductone dioxygenase [iron(II)-requiring] activity	IBA Inferred from Biological aspect of Ancestor more info
enables acireductone dioxygenase [iron(II)-requiring] activity	IEA Inferred from Electronic Annotation more info
enables dioxygenase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in methionine metabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase homolog;putative inactive acireductone dioxygenase 1

NP_001300589.1

Confirmed by transcript evidence

NP_493676.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003280.10 Reference assembly

Range

176997..179093 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_061275.9 → NP_493676.1 putative inactive acireductone dioxygenase 1 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_493676.1

Status: REVIEWED

UniProtKB/Swiss-Prot

P91416

Conserved Domains (1) summary

pfam03079
Location:2 → 158

ARD; ARD/ARD' family
NM_001313660.3 → NP_001300589.1 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase homolog [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A0K3AU20

Conserved Domains (1) summary

cl21464
Location:1 → 109

cupin_like; Conserved domain found in cupin and related proteins