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    Ccdc61 coiled-coil domain containing 61 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 292680, updated on 2-Nov-2024

    Summary

    Official Symbol
    Ccdc61provided by RGD
    Official Full Name
    coiled-coil domain containing 61provided by RGD
    Primary source
    RGD:1307390
    See related
    EnsemblRapid:ENSRNOG00000013767 AllianceGenome:RGD:1307390
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1307390
    Summary
    Predicted to enable identical protein binding activity and microtubule binding activity. Predicted to be involved in centriole assembly and mitotic spindle assembly. Predicted to be located in centriolar satellite. Predicted to be part of centriolar subdistal appendage. Predicted to be active in ciliary basal body. Orthologous to human CCDC61 (coiled-coil domain containing 61). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Adrenal (RPKM 36.7), Thymus (RPKM 32.6) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Ccdc61 in Genome Data Viewer
    Location:
    1q21
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (87665541..87685732, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (78537494..78557686, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (79796557..79816536, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120099776 Neighboring gene peptidoglycan recognition protein 1 Neighboring gene uncharacterized LOC134485103 Neighboring gene NOVA alternative splicing regulator 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables identical protein binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables microtubule binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in cell projection organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in centriole assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in centriole assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in mitotic spindle assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitotic spindle assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in centriolar satellite ISO
    Inferred from Sequence Orthology
    more info
     
    located_in centriolar satellite ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of centriolar subdistal appendage ISO
    Inferred from Sequence Orthology
    more info
     
    part_of centriolar subdistal appendage ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in centrosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in ciliary basal body IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in ciliary basal body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in ciliary basal body ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in microtubule organizing center ISO
    Inferred from Sequence Orthology
    more info
     
    located_in microtubule organizing center ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    centrosomal protein CCDC61
    Names
    VFL3 homolog
    coiled-coil domain-containing protein 61

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106229.1NP_001099699.1  centrosomal protein CCDC61

      See identical proteins and their annotated locations for NP_001099699.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473979
      UniProtKB/Swiss-Prot
      A0JPP8
      UniProtKB/TrEMBL
      A6J8I3
      Related
      ENSRNOP00000018495.6, ENSRNOT00000018495.8
      Conserved Domains (1) summary
      pfam04012
      Location:143268
      PspA_IM30; PspA/IM30 family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      87665541..87685732 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039103944.2XP_038959872.1  centrosomal protein CCDC61 isoform X1

    2. XM_039103943.2XP_038959871.1  centrosomal protein CCDC61 isoform X1