Sarnp SAP domain containing ribonucleoprotein [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Sarnpprovided by RGD
Official Full Name: SAP domain containing ribonucleoproteinprovided by RGD
Primary source: RGD:1305692
See related: EnsemblRapid:ENSRNOG00000030520 AllianceGenome:RGD:1305692
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Cip29; RGD1305692
Summary: Predicted to enable chromatin binding activity. Predicted to be involved in poly(A)+ mRNA export from nucleus. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasmic ribonucleoprotein granule and nuclear speck. Predicted to be part of transcription export complex. Predicted to be active in nucleus. Orthologous to human SARNP (SAP domain containing ribonucleoprotein). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Thymus (RPKM 123.4), Adrenal (RPKM 104.2) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 7q11

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	7	NC_086025.1 (1835597..1889833)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	7	NC_051342.1 (1251096..1305335)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	7	NC_005106.4 (3246220..3300467)

Chromosome 7 - NC_086025.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables chromatin binding	IEA Inferred from Electronic Annotation more info
enables chromatin binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in mRNA export from nucleus	IEA Inferred from Electronic Annotation more info
involved_in mRNA export from nucleus	ISO Inferred from Sequence Orthology more info
involved_in mRNA export from nucleus	ISS Inferred from Sequence or Structural Similarity more info
involved_in negative regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II	ISO Inferred from Sequence Orthology more info
involved_in poly(A)+ mRNA export from nucleus	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of translation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasmic ribonucleoprotein granule	IEA Inferred from Electronic Annotation more info
located_in cytoplasmic ribonucleoprotein granule	ISO Inferred from Sequence Orthology more info
located_in nuclear speck	IEA Inferred from Electronic Annotation more info
located_in nuclear speck	ISO Inferred from Sequence Orthology more info
located_in nuclear speck	ISS Inferred from Sequence or Structural Similarity more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	ISO Inferred from Sequence Orthology more info
part_of transcription export complex	IEA Inferred from Electronic Annotation more info
part_of transcription export complex	ISO Inferred from Sequence Orthology more info
part_of transcription export complex	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: SAP domain-containing ribonucleoprotein

Names: cytokine induced protein 29 kDa; nuclear protein Hcc-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001033070.1 → NP_001028242.1 SAP domain-containing ribonucleoprotein

See identical proteins and their annotated locations for NP_001028242.1

Status: PROVISIONAL

Source sequence(s)

BC100070

UniProtKB/Swiss-Prot

Q498U4

UniProtKB/TrEMBL

A0A8I6AC55, A6KSJ8

Related

ENSRNOP00000083779.2, ENSRNOT00000096123.2

Conserved Domains (2) summary

pfam02037
Location:8 → 42

SAP; SAP domain

pfam06884
Location:170 → 205

DUF1264; Protein of unknown function (DUF1264)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086025.1 Reference GRCr8

Range

1835597..1889833

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006240781.5 → XP_006240843.1 SAP domain-containing ribonucleoprotein isoform X1

UniProtKB/TrEMBL

A6KSJ6

Conserved Domains (2) summary

pfam02037
Location:8 → 42

SAP; SAP domain

pfam06884
Location:147 → 182

DUF1264; Protein of unknown function (DUF1264)
XM_008765031.4 → XP_008763253.1 SAP domain-containing ribonucleoprotein isoform X2

UniProtKB/TrEMBL

A6KSJ6

Conserved Domains (1) summary

pfam02037
Location:8 → 42

SAP; SAP domain
XM_063263713.1 → XP_063119783.1 SAP domain-containing ribonucleoprotein isoform X3

UniProtKB/TrEMBL

A0A8I5ZWH1, A6KSK0