Lgals8 galectin 8 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Lgals8provided by RGD
Official Full Name: galectin 8provided by RGD
Primary source: RGD:621272
See related: EnsemblRapid:ENSRNOG00000018046 AllianceGenome:RGD:621272
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable carbohydrate binding activity and integrin binding activity. Predicted to be involved in cellular response to virus; lymphatic endothelial cell migration; and xenophagy. Predicted to act upstream of or within T cell costimulation and plasma cell differentiation. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Orthologous to human LGALS8 (galectin 8). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Liver (RPKM 242.9), Testes (RPKM 208.3) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 17q12.1

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	17	NC_086035.1 (62716368..62744272)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	17	NC_051352.1 (58024652..58052764)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	17	NC_005116.4 (66487451..66515316, complement)

Chromosome 17 - NC_086035.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

D17Rat148 (e-PCR), detects polymorphism
- UniSTS:226852

RH133085 (e-PCR)
- UniSTS:216368

d17rat150 (e-PCR)
- UniSTS:121218

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables carbohydrate binding	IBA Inferred from Biological aspect of Ancestor more info
enables carbohydrate binding	IEA Inferred from Electronic Annotation more info
enables carbohydrate binding	ISO Inferred from Sequence Orthology more info
enables carbohydrate binding	ISS Inferred from Sequence or Structural Similarity more info
enables integrin binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within T cell costimulation	ISO Inferred from Sequence Orthology more info
involved_in biological_process	ND No biological Data available more info
involved_in cellular response to virus	ISO Inferred from Sequence Orthology more info
involved_in cellular response to virus	ISS Inferred from Sequence or Structural Similarity more info
involved_in lymphatic endothelial cell migration	ISO Inferred from Sequence Orthology more info
involved_in lymphatic endothelial cell migration	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within plasma cell differentiation	ISO Inferred from Sequence Orthology more info
involved_in xenophagy	ISO Inferred from Sequence Orthology more info
involved_in xenophagy	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info
located_in cytoplasmic vesicle	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in cytosol	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: galectin-8

Names: 30 kDa S-type lectin; RL-30; gal-8; lectin, galactose binding, soluble 8; lectin, galactoside-binding, soluble, 8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.