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    Zfp637 zinc finger protein 637 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362425, updated on 17-Aug-2024

    Summary

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    Official Symbol
    Zfp637provided by RGD
    Official Full Name
    zinc finger protein 637provided by RGD
    Primary source
    RGD:1559850
    See related
    EnsemblRapid:ENSRNOG00000023065 AllianceGenome:RGD:1559850
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    AZF1; DZF11
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Orthologous to human ZNF32 (zinc finger protein 32). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Brain (RPKM 141.3), Thymus (RPKM 105.7) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    4q42
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (152656937..152682499)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (150984940..151010079)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (149857127..149882828)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene enolase 1, pseudogene 20 Neighboring gene uncharacterized LOC120102373 Neighboring gene uncharacterized LOC120102374 Neighboring gene zinc finger protein 239 Neighboring gene uncharacterized LOC134486838

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. A novel profile of expressed sequence tags for zinc finger encoding genes from the poorly differentiated exocrine pancreatic cell line AR4IP. Gebelein B, et al. Cancer Lett, 1996 Aug 2. PMID 8697448
    2. Identification and characterization of zinc finger encoding genes from the tumoral exocrine pancreatic cell line AR42J. Mesa K, et al. Cancer Lett, 1996 Jun 5. PMID 8635150
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables sequence-specific double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 32
    Names
    zinc finger protein 1
    zinc finger protein 11

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001134908.1 → NP_001128380.1  zinc finger protein 32

      See identical proteins and their annotated locations for NP_001128380.1

      Status: PROVISIONAL

      Source sequence(s)
      BC158822
      UniProtKB/TrEMBL
      B0BNH4
      Related
      ENSRNOP00000101511.1, ENSRNOT00000154102.1
      Conserved Domains (3) summary
      COG5048
      Location:39 → 236
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:78 → 98
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:118 → 143
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      152656937..152682499
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006237193.5 → XP_006237255.1  zinc finger protein 32 isoform X2

      Related
      ENSRNOP00000087762.2, ENSRNOT00000104853.2
      Conserved Domains (3) summary
      COG5048
      Location:150 → 347
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:189 → 209
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:229 → 254
      zf-H2C2_2; Zinc-finger double domain

    2. XM_063286311.1 → XP_063142381.1  zinc finger protein 32 isoform X7

    3. XM_063286312.1 → XP_063142382.1  zinc finger protein 32 isoform X8

      UniProtKB/TrEMBL
      A0A8I6AKD8

    4. XM_063286320.1 → XP_063142390.1  zinc finger protein 32 isoform X16

    5. XM_063286308.1 → XP_063142378.1  zinc finger protein 32 isoform X4

      UniProtKB/TrEMBL
      A0A8I6A6H3

    6. XM_063286317.1 → XP_063142387.1  zinc finger protein 32 isoform X13

    7. XM_063286313.1 → XP_063142383.1  zinc finger protein 32 isoform X9

    8. XM_063286318.1 → XP_063142388.1  zinc finger protein 32 isoform X14

    9. XM_063286307.1 → XP_063142377.1  zinc finger protein 32 isoform X1

    10. XM_063286314.1 → XP_063142384.1  zinc finger protein 32 isoform X10

    11. XM_063286315.1 → XP_063142385.1  zinc finger protein 32 isoform X11

    12. XM_063286310.1 → XP_063142380.1  zinc finger protein 32 isoform X6

      Related
      ENSRNOP00000094186.2, ENSRNOT00000105993.2

    13. XM_039107865.2 → XP_038963793.1  zinc finger protein 32 isoform X3

      Conserved Domains (2) summary
      COG5048
      Location:138 → 335
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:177 → 197
      ZF_C2H2; C2H2 Zn finger [structural motif]

    14. XM_063286309.1 → XP_063142379.1  zinc finger protein 32 isoform X5

    15. XM_063286319.1 → XP_063142389.1  zinc finger protein 32 isoform X15

      UniProtKB/TrEMBL
      A6IL38

    16. XM_063286316.1 → XP_063142386.1  zinc finger protein 32 isoform X12

      UniProtKB/TrEMBL
      B0BNH4

    RNA

    1. XR_010065678.1 RNA Sequence

    2. XR_010065677.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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