Nmd3 NMD3 ribosome export adaptor [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Nmd3provided by RGD
Official Full Name: NMD3 ribosome export adaptorprovided by RGD
Primary source: RGD:1308468
See related: EnsemblRapid:ENSRNOG00000009310 AllianceGenome:RGD:1308468
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1308468
Summary: Predicted to enable protein-macromolecule adaptor activity and ribosomal large subunit binding activity. Predicted to be involved in several processes, including positive regulation of protein binding activity; positive regulation of protein localization to nucleolus; and ribosomal large subunit export from nucleus. Predicted to be located in nucleolus and nucleoplasm. Predicted to be active in cytoplasm and nucleus. Orthologous to human NMD3 (NMD3 ribosome export adaptor). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Heart (RPKM 232.8), Thymus (RPKM 159.1) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 2q32

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	2	NC_086020.1 (156285773..156348394)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	2	NC_051337.1 (154012973..154038466)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	2	NC_005101.4 (166402838..166428331)

Chromosome 2 - NC_086020.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables protein-macromolecule adaptor activity	ISO Inferred from Sequence Orthology more info
enables ribosomal large subunit binding	IBA Inferred from Biological aspect of Ancestor more info
enables ribosomal large subunit binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in positive regulation of RNA biosynthetic process	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of protein localization to nucleolus	ISO Inferred from Sequence Orthology more info
involved_in protein transport	IEA Inferred from Electronic Annotation more info
involved_in ribosomal large subunit export from nucleus	IBA Inferred from Biological aspect of Ancestor more info
involved_in ribosomal large subunit export from nucleus	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in nucleolus	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: 60S ribosomal export protein NMD3

Names: NMD3 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001107682.2 → NP_001101152.1 60S ribosomal export protein NMD3

See identical proteins and their annotated locations for NP_001101152.1

Status: VALIDATED

Source sequence(s)

BC161998

UniProtKB/TrEMBL

A0A9K3Y797, A6J5N6, B1WC44, F7ERL4

Related

ENSRNOP00000012417.8, ENSRNOT00000012417.9

Conserved Domains (1) summary

pfam04981
Location:17 → 246

NMD3; NMD3 family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086020.1 Reference GRCr8

Range

156285773..156348394

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063281803.1 → XP_063137873.1 60S ribosomal export protein NMD3 isoform X1

UniProtKB/TrEMBL

A0A9K3Y797, A6J5N6, B1WC44, F7ERL4
XM_063281802.1 → XP_063137872.1 60S ribosomal export protein NMD3 isoform X1

UniProtKB/TrEMBL

A0A9K3Y797, A6J5N6, B1WC44, F7ERL4
XM_039102292.2 → XP_038958220.1 60S ribosomal export protein NMD3 isoform X1

UniProtKB/TrEMBL

A0A9K3Y797, A6J5N6, B1WC44, F7ERL4

Conserved Domains (1) summary

pfam04981
Location:17 → 246

NMD3; NMD3 family
XM_039102293.2 → XP_038958221.1 60S ribosomal export protein NMD3 isoform X3

Conserved Domains (1) summary

pfam04981
Location:1 → 126

NMD3; NMD3 family
XM_063281804.1 → XP_063137874.1 60S ribosomal export protein NMD3 isoform X2