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    gar-1 G-protein coupled receptors family 1 profile domain-containing protein;putative muscarinic acetylcholine receptor gar-1 [ Caenorhabditis elegans ]

    Gene ID: 180922, updated on 2-Nov-2024

    Summary

    Official Symbol
    gar-1
    Official Full Name
    G-protein coupled receptors family 1 profile domain-containing protein;putative muscarinic acetylcholine receptor gar-1
    Primary source
    WormBase:WBGene00001517
    Locus tag
    CELE_C15B12.5
    See related
    AllianceGenome:WB:WBGene00001517
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables G protein-coupled acetylcholine receptor activity. Involved in cholinergic synaptic transmission. Located in postsynaptic membrane. Is expressed in PVM and head neurons. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See gar-1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    18
    Sequence:
    Chromosome: X; NC_003284.9 (6479443..6484880, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene FAD dependent oxidoreductase domain-containing protein Neighboring gene Putative sarcosine oxidase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables G protein-coupled acetylcholine receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables G protein-coupled acetylcholine receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables G protein-coupled acetylcholine receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables G protein-coupled amine receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in dendrite IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in postsynaptic membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in synapse IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    G-protein coupled receptors family 1 profile domain-containing protein;putative muscarinic acetylcholine receptor gar-1
    NP_001024401.1
    • Partially confirmed by transcript evidence
    NP_001024402.1
    • Partially confirmed by transcript evidence
    NP_001024403.1
    • Partially confirmed by transcript evidence
    NP_001360659.1
    • Partially confirmed by transcript evidence
    NP_001360660.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      6479443..6484880 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001029230.3NP_001024401.1  putative muscarinic acetylcholine receptor gar-1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001024401.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q18007
      Conserved Domains (2) summary
      pfam00001
      Location:41236
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:39163
      7tm_4; Olfactory receptor
    2. NM_001029231.3NP_001024402.1  putative muscarinic acetylcholine receptor gar-1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001024402.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q18007, Q9NJS7, Q9NJS8, Q9XTK1
      Conserved Domains (2) summary
      pfam00001
      Location:41236
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:39163
      7tm_4; Olfactory receptor
    3. NM_001029232.2NP_001024403.1  putative muscarinic acetylcholine receptor gar-1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001024403.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q18007
      Conserved Domains (2) summary
      pfam00001
      Location:41236
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:39163
      7tm_4; Olfactory receptor
    4. NM_001373329.1NP_001360660.1  G-protein coupled receptors family 1 profile domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A4V0ILB0
      Conserved Domains (2) summary
      cd14964
      Location:6086
      7tm_GPCRs; TM helix 2 [structural motif]
      cl28897
      Location:34236
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    5. NM_001373330.1NP_001360659.1  G-protein coupled receptors family 1 profile domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A4V0IIV3
      Conserved Domains (3) summary
      cd15302
      Location:34236
      7tmA_mAChR_GAR-2-like; muscarinic acetylcholine receptor GAR-2 and similar proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
      cd14964
      Location:626656
      7tm_GPCRs; TM helix 6 [structural motif]
      cl28897
      Location:623698
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily