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    trap-3 Translocon-associated protein subunit gamma [ Caenorhabditis elegans ]

    Gene ID: 177028, updated on 2-Nov-2024

    Summary

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    Official Symbol
    trap-3
    Official Full Name
    Translocon-associated protein subunit gamma
    Primary source
    WormBase:WBGene00021420
    Locus tag
    CELE_Y38F2AR.2
    See related
    AllianceGenome:WB:WBGene00021420
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum. Orthologous to human SSR3 (signal sequence receptor subunit 3). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See trap-3 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    3
    Sequence:
    Chromosome: IV; NC_003282.8 (2389445..2390259)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Protein transport protein Sec61 subunit beta Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Protein kinase domain-containing protein;Tudor domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular basis of the TRAP complex function in ER protein biogenesis. Jaskolowski M, et al. Nat Struct Mol Biol, 2023 Jun. PMID 37170030, Free PMC Article
    2. CCAR-1 works together with the U2AF large subunit UAF-1 to regulate alternative splicing. Lugano DI, et al. RNA Biol, 2024 Jan. PMID 38126797, Free PMC Article
    3. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
    4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in SRP-dependent cotranslational protein targeting to membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Translocon-associated protein subunit gamma
    NP_500198.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      2389445..2390259
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067797.8 → NP_500198.1  Translocon-associated protein subunit gamma [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500198.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95XS1
      Conserved Domains (1) summary
      pfam07074
      Location:7 → 176
      TRAP-gamma; Translocon-associated protein, gamma subunit (TRAP-gamma)
    Nucleotide Protein
    Heading Accession and Version

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