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    nmtn-1 CTLH domain-containing protein;WD_REPEATS_REGION domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 172355, updated on 2-Nov-2024

    Summary

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    Official Symbol
    nmtn-1
    Official Full Name
    CTLH domain-containing protein;WD_REPEATS_REGION domain-containing protein
    Primary source
    WormBase:WBGene00019434
    Locus tag
    CELE_K06A5.8
    See related
    AllianceGenome:WB:WBGene00019434
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Orthologous to human WDR47 (WD repeat domain 47). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See nmtn-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    18
    Sequence:
    Chromosome: I; NC_003279.8 (6473860..6488977, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Major sperm protein Neighboring gene DUF389 domain membrane protein Neighboring gene M-phase inducer phosphatase cdc-25.1 Neighboring gene Chromo domain-containing protein Neighboring gene STAS domain-containing protein Neighboring gene ncRNA Neighboring gene Lariat debranching enzyme Neighboring gene Mediator of RNA polymerase II transcription subunit 18 Neighboring gene Unconventional prefoldin RPB5 interactor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Nemitin, a novel Map8/Map1s interacting protein with Wd40 repeats. Wang W, et al. PLoS One, 2012. PMID 22523538, Free PMC Article
    2. A WDR47 homolog facilitates ciliogenesis by modulating intraflagellar transport. Song CX, et al. J Cell Sci, 2022 Dec 15. PMID 36453135
    3. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    CTLH domain-containing protein;WD_REPEATS_REGION domain-containing protein
    NP_001370607.1
    • Confirmed by transcript evidence
    NP_491864.2
    • Confirmed by transcript evidence
    NP_491865.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      6473860..6488977 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001383257.1 → NP_001370607.1  WD_REPEATS_REGION domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KZG8
      Conserved Domains (2) summary
      sd00039
      Location:363 → 412
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:411 → 559
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    2. NM_059463.8 → NP_491864.2  CTLH domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491864.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KZG7
      Conserved Domains (3) summary
      smart00668
      Location:62 → 118
      CTLH; C-terminal to LisH motif
      cd00200
      Location:679 → 939
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:683 → 724
      7WD40; WD40 repeat [structural motif]

    3. NM_059464.5 → NP_491865.2  CTLH domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491865.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95X65
      Conserved Domains (3) summary
      smart00668
      Location:62 → 118
      CTLH; C-terminal to LisH motif
      sd00039
      Location:629 → 678
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:677 → 861
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version

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