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    pigb-1 Mannosyltransferase [ Caenorhabditis elegans ]

    Gene ID: 13184808, updated on 2-Nov-2024

    Summary

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    Official Symbol
    pigb-1
    Official Full Name
    Mannosyltransferase
    Primary source
    WormBase:WBGene00194986
    Locus tag
    CELE_T27F7.4
    See related
    AllianceGenome:WB:WBGene00194986
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable alpha-1,2-mannosyltransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 80. Orthologous to human PIGB (phosphatidylinositol glycan anchor biosynthesis class B). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See pigb-1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003280.10 (4991587..4993077, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene SH2 domain-containing protein Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene SUI1 domain-containing protein Neighboring gene Charged multivesicular body protein 3 Neighboring gene Ribonuclease H1;Ribonuclease H1 N-terminal domain-containing protein Neighboring gene Conserved secreted protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables alpha-1,2-mannosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in GPI anchor biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Mannosyltransferase
    NP_001254097.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      4991587..4993077 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001267168.1 → NP_001254097.1  Mannosyltransferase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001254097.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EDN2
      Conserved Domains (1) summary
      cl21590
      Location:1 → 425
      PMT_2; Dolichyl-phosphate-mannose-protein mannosyltransferase
    Nucleotide Protein
    Heading Accession and Version

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