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    pals-25 Protein containing ALS2cr12 (ALS2CR12) signature [ Caenorhabditis elegans ]

    Gene ID: 188564, updated on 2-Nov-2024

    Summary

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    Official Symbol
    pals-25
    Official Full Name
    Protein containing ALS2cr12 (ALS2CR12) signature
    Primary source
    WormBase:WBGene00020540
    Locus tag
    CELE_T17A3.2
    See related
    AllianceGenome:WB:WBGene00020540
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Is expressed in several structures, including hypodermis; intestine; nervous system; and pharynx. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See pals-25 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    5
    Sequence:
    Chromosome: III; NC_003281.10 (134494..137975)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Retrotrans_gag domain-containing protein Neighboring gene F-box associated domain-containing protein Neighboring gene F-box domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Antagonistic paralogs control a switch between growth and pathogen resistance in C. elegans. Reddy KC, et al. PLoS Pathog, 2019 Jan. PMID 30640956, Free PMC Article
    2. Balancing Selection of the Intracellular Pathogen Response in Natural Caenorhabditis elegans Populations. van Sluijs L, et al. Front Cell Infect Microbiol, 2021. PMID 35174100, Free PMC Article
    3. A pals-25 gain-of-function allele triggers systemic resistance against natural pathogens of C. elegans. Gang SS, et al. PLoS Genet, 2022 Oct. PMID 36191002, Free PMC Article
    4. A cullin-RING ubiquitin ligase promotes thermotolerance as part of the intracellular pathogen response in Caenorhabditis elegans. Panek J, et al. Proc Natl Acad Sci U S A, 2020 Apr 7. PMID 32193347, Free PMC Article
    5. Heat Stress Reduces the Susceptibility of Caenorhabditis elegans to Orsay Virus Infection. Huang Y, et al. Genes (Basel), 2021 Jul 28. PMID 34440335, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    General protein information

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    Preferred Names
    Protein containing ALS2cr12 (ALS2CR12) signature
    NP_497153.2
    • Confirmed by transcript evidence;
      Product from WormBase gene class pals

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      134494..137975
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_064752.5 → NP_497153.2  Protein containing ALS2cr12 (ALS2CR12) signature [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497153.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      G4S455, Q3V5H4
    Nucleotide Protein
    Heading Accession and Version

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