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    • Showing Current items.

    K05B2.4 Acyl-coenzyme A thioesterase 1-like [ Caenorhabditis elegans ]

    Gene ID: 187017, updated on 2-Nov-2024

    Summary

    Official Symbol
    K05B2.4
    Official Full Name
    Acyl-coenzyme A thioesterase 1-like
    Primary source
    WormBase:WBGene00019404
    Locus tag
    CELE_K05B2.4
    See related
    AllianceGenome:WB:WBGene00019404
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable fatty acyl-CoA hydrolase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid metabolic process. Human ortholog(s) of this gene implicated in disease of metabolism. Orthologous to several human genes including ACOT1 (acyl-CoA thioesterase 1); ACOT2 (acyl-CoA thioesterase 2); and ACOT4 (acyl-CoA thioesterase 4). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See K05B2.4 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    9
    Sequence:
    Chromosome: X; NC_003284.9 (4918988..4920992, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene RAB6-interacting golgin;Ras-associating domain-containing protein Neighboring gene Intermediate filament protein ifa-4 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene MFS domain-containing protein;Major facilitator superfamily (MFS) profile domain-containing protein Neighboring gene ncRNA

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables fatty acyl-CoA hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables thiolester hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in acyl-CoA metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in acyl-CoA metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in fatty acid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Acyl-coenzyme A thioesterase 1-like
    NP_508837.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      4918988..4920992 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_076436.5NP_508837.3  Acyl-coenzyme A thioesterase 1-like [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508837.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9GYN3
      Conserved Domains (2) summary
      pfam04775
      Location:16133
      Bile_Hydr_Trans; Acyl-CoA thioester hydrolase/BAAT N-terminal region
      pfam08840
      Location:208417
      BAAT_C; BAAT / Acyl-CoA thioester hydrolase C terminal