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    wdr-83 WD repeat domain-containing protein 83 [ Caenorhabditis elegans ]

    Gene ID: 173867, updated on 2-Nov-2024

    Summary

    Official Symbol
    wdr-83
    Official Full Name
    WD repeat domain-containing protein 83
    Primary source
    WormBase:WBGene00018014
    Locus tag
    CELE_F33G12.2
    See related
    AllianceGenome:WB:WBGene00018014
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in cytoplasm. Predicted to be part of catalytic step 2 spliceosome. Orthologous to human WDR83 (WD repeat domain 83). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See wdr-83 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    6
    Sequence:
    Chromosome: II; NC_003280.10 (5029944..5031712, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene 50S ribosomal protein L29 Neighboring gene Uncharacterized protein Neighboring gene Mitogen-activated protein kinase kinase kinase nsy-1;mitogen-activated protein kinase kinase kinase Neighboring gene DUF1308 domain-containing protein Neighboring gene tRNA-Ile Neighboring gene Leucine-Rich Repeat protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    WD repeat domain-containing protein 83
    NP_494926.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      5029944..5031712 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_062525.6NP_494926.1  WD repeat domain-containing protein 83 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_494926.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q19986
      Conserved Domains (2) summary
      cd00200
      Location:10294
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:2156
      7WD40; WD40 repeat [structural motif]