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    W03F9.1 Zinc finger ZPR1-type domain-containing protein;Zinc finger protein ZPR1 homolog [ Caenorhabditis elegans ]

    Gene ID: 189162, updated on 2-Nov-2024

    Summary

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    Official Symbol
    W03F9.1
    Official Full Name
    Zinc finger ZPR1-type domain-containing protein;Zinc finger protein ZPR1 homolog
    Primary source
    WormBase:WBGene00020999
    Locus tag
    CELE_W03F9.1
    See related
    AllianceGenome:WB:WBGene00020999
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein folding chaperone. Predicted to be involved in protein folding. Located in endoplasmic reticulum; sarcomere; and striated muscle dense body. Orthologous to human ZPR1 (ZPR1 zinc finger). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See W03F9.1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    5
    Sequence:
    Chromosome: V; NC_003283.11 (124010..126718, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Small ribosomal subunit protein eS27 Neighboring gene Pry-1 Interacting and CABIN1 Domain containing Neighboring gene GTP-binding protein cgp-1;GTP_EFTU_D3 domain-containing protein Neighboring gene C2H2-type domain-containing protein Neighboring gene PSP proline-rich domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
    2. SIN-3 acts in distinct complexes to regulate the germline transcriptional program in Caenorhabditis elegans. Robert VJ, et al. Development, 2023 Nov 1. PMID 37818613, Free PMC Article
    3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein folding chaperone ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein folding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in sarcomere HDA PubMed 
    located_in striated muscle dense body HDA PubMed 

    General protein information

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    Preferred Names
    Zinc finger ZPR1-type domain-containing protein;Zinc finger protein ZPR1 homolog
    NP_001300211.1
    • Confirmed by transcript evidence
    NP_503138.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      124010..126718 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_070737.5 → NP_503138.1  Zinc finger protein ZPR1 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_503138.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O16999
      Conserved Domains (1) summary
      smart00709
      Location:26 → 184
      Zpr1; Duplicated domain in the epidermal growth factor- and elongation factor-1alpha-binding protein Zpr1. Also present in archaeal proteins

    2. NM_001313282.3 → NP_001300211.1  Zinc finger ZPR1-type domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3AV63
      Conserved Domains (1) summary
      cl19251
      Location:3 → 45
      zf-ZPR1; ZPR1 zinc-finger domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O16999.2

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