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    K02D10.1 Glycerol-3-phosphate phosphatase;Putative NipSnap protein K02D10.1 [ Caenorhabditis elegans ]

    Gene ID: 176232, updated on 2-Nov-2024

    Summary

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    Official Symbol
    K02D10.1
    Official Full Name
    Glycerol-3-phosphate phosphatase;Putative NipSnap protein K02D10.1
    Primary source
    WormBase:WBGene00019301
    Locus tag
    CELE_K02D10.1
    See related
    AllianceGenome:WB:WBGene00019301
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable metal ion binding activity and phosphatase activity. Predicted to be active in mitochondrion. Is expressed in hypodermis. Orthologous to human NIPSNAP1 (nipsnap homolog 1) and NIPSNAP2 (nipsnap homolog 2). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See K02D10.1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    6
    Sequence:
    Chromosome: III; NC_003281.10 (8769536..8776147)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Chondroitin sulfate synthase mig-22 Neighboring gene Single-stranded DNA-binding protein, mitochondrial Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene Soluble NSF attachment protein 29 Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The conserved histone chaperone LIN-53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans. Müthel S, et al. Aging Cell, 2019 Dec. PMID 31397537, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Glycerol-3-phosphate phosphatase;Putative NipSnap protein K02D10.1
    NP_001367889.1
    • Partially confirmed by transcript evidence
    NP_001379980.1
    • Confirmed by transcript evidence
    NP_498939.3
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      8769536..8776147
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001392163.1 → NP_001379980.1  Putative NipSnap protein K02D10.1 [Caenorhabditis elegans]

      Status: REVIEWED

      Conserved Domains (1) summary
      pfam07978
      Location:190 → 287
      NIPSNAP

    2. NM_001379847.2 → NP_001367889.1  Glycerol-3-phosphate phosphatase [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A9Z1J6
      Conserved Domains (1) summary
      cd07532
      Location:10 → 283
      HAD_PNPase_UmpH-like; UmpH/NagD family phosphatase para nitrophenyl phosphate phosphatase, similar to Plasmodium falciparum PNPase

    3. NM_066538.4 → NP_498939.3  Putative NipSnap protein K02D10.1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498939.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O61223, P34492, Q95QD2
      Conserved Domains (4) summary
      TIGR01460
      Location:18 → 264
      HAD-SF-IIA; Haloacid Dehalogenase Superfamily Class (subfamily) IIA
      pfam07978
      Location:427 → 524
      NIPSNAP; NIPSNAP
      pfam13242
      Location:219 → 260
      Hydrolase_like; HAD-hyrolase-like
      pfam13344
      Location:18 → 121
      Hydrolase_6; Haloacid dehalogenase-like hydrolase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P34492.4

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