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    sap-140 U2 snRNP-associated SURP motif-containing protein [ Caenorhabditis elegans ]

    Gene ID: 176063, updated on 18-Sep-2024

    Summary

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    Official Symbol
    sap-140
    Official Full Name
    U2 snRNP-associated SURP motif-containing protein
    Primary source
    WormBase:WBGene00015581
    Locus tag
    CELE_C07H6.4
    See related
    AllianceGenome:WB:WBGene00015581
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in RNA processing. Orthologous to human U2SURP (U2 snRNP associated SURP domain containing). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See sap-140 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    8
    Sequence:
    Chromosome: III; NC_003281.10 (7499738..7503241)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ATP-dependent RNA helicase cgh-1 Neighboring gene ncRNA Neighboring gene Serpentine Receptor, class Z Neighboring gene Protein CLASP-1 Neighboring gene Telomere length regulation protein clk-2 Neighboring gene RRM domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    U2 snRNP-associated SURP motif-containing protein
    NP_498648.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      7499738..7503241
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066247.7 → NP_498648.1  U2 snRNP-associated SURP motif-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498648.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95YF1
      Conserved Domains (3) summary
      cd12223
      Location:199 → 282
      RRM_SR140; RNA recognition motif (RRM) in U2-associated protein SR140 and similar proteins
      pfam01805
      Location:366 → 416
      Surp; Surp module
      cl02544
      Location:529 → 665
      VHS_ENTH_ANTH; VHS, ENTH and ANTH domain superfamily; composed of proteins containing a VHS, ENTH or ANTH domain. The VHS domain is present in Vps27 (Vacuolar Protein Sorting), Hrs (Hepatocyte growth factor-regulated tyrosine kinase substrate) and STAM (Signal ...
    Nucleotide Protein
    Heading Accession and Version

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