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    F31E3.2 Putative serine/threonine-protein kinase F31E3.2 [ Caenorhabditis elegans ]

    Gene ID: 175977, updated on 12-Jun-2024

    Summary

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    Gene symbol
    F31E3.2
    Gene description
    Putative serine/threonine-protein kinase F31E3.2
    Locus tag
    CELE_F31E3.2
    See related
    AllianceGenome:WB:WBGene00017950
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein kinase activity. Predicted to be involved in protein phosphorylation. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma. Orthologous to several human genes including PBX2 (PBX homeobox 2); PBX3 (PBX homeobox 3); and RSKR (ribosomal protein S6 kinase related). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See F31E3.2 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    10
    Sequence:
    Chromosome: III; NC_003281.10 (6973982..6978025)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Replication factor C subunit 4 Neighboring gene Homeobox protein ceh-20 Neighboring gene ncRNA Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The roles of two C. elegans HOX co-factor orthologs in cell migration and vulva development. Yang L, et al. Development, 2005 Mar. PMID 15750187
    2. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Functions independently of lin-39 in vulva development.
      Title: The roles of two C. elegans HOX co-factor orthologs in cell migration and vulva development.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Putative serine/threonine-protein kinase F31E3.2
    NP_001022557.1
    • Confirmed by transcript evidence
    NP_001022558.1
    • Confirmed by transcript evidence
    NP_498522.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      6973982..6978025
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001027386.6 → NP_001022557.1  Putative serine/threonine-protein kinase F31E3.2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001022557.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8MYQ1
      Conserved Domains (2) summary
      smart00220
      Location:126 → 381
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05123
      Location:132 → 381
      STKc_AGC; Catalytic domain of AGC family Serine/Threonine Kinases

    2. NM_066121.6 → NP_498522.3  Putative serine/threonine-protein kinase F31E3.2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498522.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8MYQ1, Q8MYQ2, Q95QH8
      Conserved Domains (2) summary
      smart00220
      Location:126 → 381
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05123
      Location:132 → 381
      STKc_AGC; Catalytic domain of AGC family Serine/Threonine Kinases

    3. NM_001027387.4 → NP_001022558.1  Putative serine/threonine-protein kinase F31E3.2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001022558.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8MYQ1
      Conserved Domains (1) summary
      cl18951
      Location:26 → 92
      Amidase; Amidase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MYQ1.1

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