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    W07E11.1 glutamate synthase (NADH) [ Caenorhabditis elegans ]

    Gene ID: 181223, updated on 2-Nov-2024

    Summary

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    Official Symbol
    W07E11.1
    Official Full Name
    glutamate synthase (NADH)
    Primary source
    WormBase:WBGene00012326
    Locus tag
    CELE_W07E11.1
    See related
    AllianceGenome:WB:WBGene00012326
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable glutamate synthase (NADH) activity. Predicted to be involved in ammonia assimilation cycle and glutamate biosynthetic process. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See W07E11.1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    19
    Sequence:
    Chromosome: X; NC_003284.9 (10084622..10104650)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene FMRF-Like Peptide Neighboring gene TPLGTMRF-amide Neighboring gene SPREPIRF-amide Neighboring gene ncRNA Neighboring gene Potassium channel domain-containing protein;Uncoordinated protein 58 Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of the intracellular neurexin interactome by in vivo proximity ligation suggests its involvement in presynaptic actin assembly. Schaan Profes M, et al. PLoS Biol, 2024 Jan. PMID 38252619, Free PMC Article
    2. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
    3. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
    4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables 3 iron, 4 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables FMN binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables flavin adenine dinucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glutamate synthase (NADH) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glutamate synthase (NADH) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glutamate synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron-sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on the CH-NH2 group of donors IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in L-glutamate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in ammonia assimilation cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in glutamate biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in glutamate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in glutamine metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    glutamate synthase (NADH)
    NP_001263967.1
    • Confirmed by transcript evidence
    NP_001369873.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      10084622..10104650
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001383634.1 → NP_001369873.1  glutamate synthase (NADH) [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EF05
      Conserved Domains (3) summary
      PRK11750
      Location:15 → 1511
      gltB; glutamate synthase subunit alpha; Provisional
      PRK12810
      Location:1671 → 2158
      gltD; glutamate synthase subunit beta; Reviewed
      pfam17380
      Location:1505 → 1690
      DUF5401; Family of unknown function (DUF5401)

    2. NM_001277038.5 → NP_001263967.1  glutamate synthase (NADH) [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001263967.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      K8F7V7
      Conserved Domains (3) summary
      PRK11750
      Location:15 → 1521
      gltB; glutamate synthase subunit alpha; Provisional
      PRK12810
      Location:1681 → 2168
      gltD; glutamate synthase subunit beta; Reviewed
      pfam17380
      Location:1515 → 1700
      DUF5401; Family of unknown function (DUF5401)
    Nucleotide Protein
    Heading Accession and Version

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