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    tes-1 uncharacterized protein [ Caenorhabditis elegans ]

    Gene ID: 177515, updated on 2-Nov-2024

    Summary

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    Official Symbol
    tes-1
    Official Full Name
    uncharacterized protein
    Primary source
    WormBase:WBGene00015217
    Locus tag
    CELE_B0496.8
    See related
    AllianceGenome:WB:WBGene00015217
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable zinc ion binding activity. Is expressed in several structures, including AB; cuticular ala; hypodermal cell; nervous system; and reproductive system. Orthologous to human LMCD1 (LIM and cysteine rich domains 1) and TES (testin LIM domain protein). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See tes-1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    5
    Sequence:
    Chromosome: IV; NC_003282.8 (7449066..7451445, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene BTB domain-containing protein Neighboring gene BTB domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TES-1/Tes and ZYX-1/Zyxin protect junctional actin networks under tension during epidermal morphogenesis in the C. elegans embryo. Lynch AM, et al. Curr Biol, 2022 Dec 5. PMID 36384139, Free PMC Article
    2. Mass spectrometry-based shotgun proteomic analysis of C. elegans protein complexes. Fonslow BR, et al. WormBook, 2014 Jun 24. PMID 24967700, Free PMC Article
    3. A novel noncanonical Wnt pathway is involved in the regulation of the asymmetric B cell division in C. elegans. Wu M, et al. Dev Biol, 2006 May 15. PMID 16631156
    4. Adult-restricted gene knock-down reveals candidates that affect locomotive healthspan in C. elegans. Jushaj A, et al. Biogerontology, 2023 Apr. PMID 36662373
    5. Transcriptional regulation. Okkema PG, et al. WormBook, 2005 Dec 23. PMID 18050428, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    NP_501190.1
    • Product from WormBase gene class tes;
      Confirmed by transcript evidence; TEStin (human testis-derived transcript) homolog

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      7449066..7451445 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_068789.6 → NP_501190.1  uncharacterized protein CELE_B0496.8 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501190.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q17525
      Conserved Domains (4) summary
      cd09340
      Location:272 → 329
      LIM1_Testin_like; The first LIM domain of Testin-like family
      cd09341
      Location:335 → 389
      LIM2_Testin_like; The second LIM domain of Testin-like family
      cd09342
      Location:397 → 453
      LIM3_Testin_like; The third LIM domain of Testin-like family
      cd09829
      Location:153 → 239
      PET_testin; The PET domain of Testin
    Nucleotide Protein
    Heading Accession and Version

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