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    nhr-219 Nuclear Hormone Receptor family [ Caenorhabditis elegans ]

    Gene ID: 3565145, updated on 2-Nov-2024

    Summary

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    Official Symbol
    nhr-219
    Official Full Name
    Nuclear Hormone Receptor family
    Primary source
    WormBase:WBGene00020555
    Locus tag
    CELE_T19A5.5
    See related
    AllianceGenome:WB:WBGene00020555
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in ciliated neurons; head neurons; pharynx; and sensory neurons. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See nhr-219 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    6
    Sequence:
    Chromosome: V; NC_003283.11 (8964662..8966186, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Germinal center kinase 1;non-specific serine/threonine protein kinase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene TPR_REGION domain-containing protein Neighboring gene Nuclear hormone receptor family member nhr-44 Neighboring gene pseudo Neighboring gene NR LBD domain-containing protein;Nuclear receptor domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. CEST-2.2 overexpression alters lipid metabolism and extends longevity of mitochondrial mutants. Piazzesi A, et al. EMBO Rep, 2022 May 4. PMID 35297148, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Nuclear Hormone Receptor family
    NP_001309650.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      8964662..8966186 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001322579.3 → NP_001309650.1  Nuclear Hormone Receptor family [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A131MCX9
      Conserved Domains (2) summary
      smart00399
      Location:23 → 94
      ZnF_C4; c4 zinc finger in nuclear hormone receptors
      pfam00104
      Location:178 → 381
      Hormone_recep; Ligand-binding domain of nuclear hormone receptor
    Nucleotide Protein
    Heading Accession and Version

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