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    dhs-18 Hydroxysteroid dehydrogenase-like protein 2 [ Caenorhabditis elegans ]

    Gene ID: 179529, updated on 2-Nov-2024

    Summary

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    Official Symbol
    dhs-18
    Official Full Name
    Hydroxysteroid dehydrogenase-like protein 2
    Primary source
    WormBase:WBGene00000981
    Locus tag
    CELE_C45B11.3
    See related
    AllianceGenome:WB:WBGene00000981
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be active in mitochondrion. Orthologous to human HSDL2 (hydroxysteroid dehydrogenase like 2). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See dhs-18 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    3
    Sequence:
    Chromosome: V; NC_003283.11 (11045705..11046833, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene Epoxide hydrolase Neighboring gene Serpentine Receptor, class H Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. New Roles for the Heterochronic Transcription Factor LIN-29 in Cuticle Maintenance and Lipid Metabolism at the Larval-to-Adult Transition in Caenorhabditis elegans. Abete-Luzi P, et al. Genetics, 2020 Mar. PMID 31974205, Free PMC Article
    2. Functional identification of microRNA-centered complexes in C. elegans. Hebbar S, et al. Sci Rep, 2022 May 3. PMID 35504914, Free PMC Article
    3. RNA targets and specificity of Staufen, a double-stranded RNA-binding protein in Caenorhabditis elegans. LeGendre JB, et al. J Biol Chem, 2013 Jan 25. PMID 23195953, Free PMC Article
    4. Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. Zhang Y, et al. BMC Genomics, 2013 Mar 12. PMID 23496871, Free PMC Article
    5. Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules. Marnik EA, et al. Genetics, 2019 Nov. PMID 31506335, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Hydroxysteroid dehydrogenase-like protein 2
    NP_505812.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      11045705..11046833 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_073411.9 → NP_505812.1  Hydroxysteroid dehydrogenase-like protein 2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_505812.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q18639
      Conserved Domains (2) summary
      PRK08278
      Location:11 → 279
      PRK08278; short chain dehydrogenase; Provisional
      pfam00106
      Location:14 → 201
      adh_short; short chain dehydrogenase
    Nucleotide Protein
    Heading Accession and Version

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