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    copg-1 Coatomer subunit gamma;putative coatomer subunit gamma [ Caenorhabditis elegans ]

    Gene ID: 177891, updated on 2-Nov-2024

    Summary

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    Official Symbol
    copg-1
    Official Full Name
    Coatomer subunit gamma;putative coatomer subunit gamma
    Primary source
    WormBase:WBGene00011775
    Locus tag
    CELE_T14G10.5
    See related
    AllianceGenome:WB:WBGene00011775
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable structural molecule activity. Predicted to be involved in Golgi vesicle transport; organelle transport along microtubule; and protein secretion. Predicted to be located in COPI-coated vesicle membrane and Golgi apparatus. Predicted to be part of COPI vesicle coat. Predicted to be active in Golgi membrane; endoplasmic reticulum; and endoplasmic reticulum-Golgi intermediate compartment. Orthologous to human COPG1 (COPI coat complex subunit gamma 1) and COPG2 (COPI coat complex subunit gamma 2). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See copg-1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    7
    Sequence:
    Chromosome: IV; NC_003282.8 (10151947..10155639)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Tetraspanin-12 Neighboring gene ncRNA Neighboring gene Transthyretin-like family protein Neighboring gene Transthyretin-like family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. AP-1 Recruits SMAP-1/SMAPs to the trans-Golgi Network to Promote Sorting in Polarized Epithelia. Wang S, et al. Front Cell Dev Biol, 2021. PMID 34901019, Free PMC Article
    2. AdipoR2 recruits protein interactors to promote fatty acid elongation and membrane fluidity. Ruiz M, et al. J Biol Chem, 2023 Jun. PMID 37164154, Free PMC Article
    3. Caenorhabditis elegans ALG-1 antimorphic mutations uncover functions for Argonaute in microRNA guide strand selection and passenger strand disposal. Zinovyeva AY, et al. Proc Natl Acad Sci U S A, 2015 Sep 22. PMID 26351692, Free PMC Article
    4. The conserved histone chaperone LIN-53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans. Müthel S, et al. Aging Cell, 2019 Dec. PMID 31397537, Free PMC Article
    5. The RNA-binding protein repertoire of Arabidopsis thaliana. Marondedze C, et al. Sci Rep, 2016 Jul 11. PMID 27405932, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables structural molecule activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in intra-Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in organelle transport along microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein secretion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of COPI vesicle coat IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of COPI vesicle coat IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in COPI-coated vesicle membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in endoplasmic reticulum-Golgi intermediate compartment IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of membrane coat IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Coatomer subunit gamma;putative coatomer subunit gamma
    NP_001040988.1
    • Confirmed by transcript evidence
    NP_001040989.1
    • Confirmed by transcript evidence
    NP_001255464.1
    • Confirmed by transcript evidence
    NP_001293961.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      10151947..10155639
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001268535.4 → NP_001255464.1  Coatomer subunit gamma [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255464.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F5GUA3
      Conserved Domains (5) summary
      COG5240
      Location:14 → 881
      SEC21; Vesicle coat complex COPI, gamma subunit [Intracellular trafficking and secretion]
      pfam08752
      Location:624 → 767
      COP-gamma_platf; Coatomer gamma subunit appendage platform subdomain
      pfam12830
      Location:305 → 358
      Nipped-B_C; Sister chromatid cohesion C-terminus
      pfam16381
      Location:769 → 884
      Coatomer_g_Cpla; Coatomer subunit gamma-1 C-terminal appendage platform
      sd00044
      Location:408 → 433
      HEAT; HEAT repeat [structural motif]

    2. NM_001047524.5 → NP_001040989.1  Coatomer subunit gamma [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001040989.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2XN02
      Conserved Domains (5) summary
      COG5240
      Location:14 → 879
      SEC21; Vesicle coat complex COPI, gamma subunit [Intracellular trafficking and secretion]
      pfam08752
      Location:622 → 765
      COP-gamma_platf; Coatomer gamma subunit appendage platform subdomain
      pfam12830
      Location:303 → 356
      Nipped-B_C; Sister chromatid cohesion C-terminus
      pfam16381
      Location:767 → 882
      Coatomer_g_Cpla; Coatomer subunit gamma-1 C-terminal appendage platform
      sd00044
      Location:406 → 431
      HEAT; HEAT repeat [structural motif]

    3. NM_001047523.6 → NP_001040988.1  putative coatomer subunit gamma [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001040988.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q22498
      Conserved Domains (5) summary
      COG5240
      Location:1 → 866
      SEC21; Vesicle coat complex COPI, gamma subunit [Intracellular trafficking and secretion]
      pfam08752
      Location:609 → 752
      COP-gamma_platf; Coatomer gamma subunit appendage platform subdomain
      pfam12830
      Location:290 → 343
      Nipped-B_C; Sister chromatid cohesion C-terminus
      pfam16381
      Location:754 → 869
      Coatomer_g_Cpla; Coatomer subunit gamma-1 C-terminal appendage platform
      sd00044
      Location:393 → 418
      HEAT; HEAT repeat [structural motif]

    4. NM_001307032.3 → NP_001293961.1  Coatomer subunit gamma [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293961.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A061ACR1
      Conserved Domains (5) summary
      COG5240
      Location:1 → 868
      SEC21; Vesicle coat complex COPI, gamma subunit [Intracellular trafficking and secretion]
      pfam08752
      Location:611 → 754
      COP-gamma_platf; Coatomer gamma subunit appendage platform subdomain
      pfam12830
      Location:292 → 345
      Nipped-B_C; Sister chromatid cohesion C-terminus
      pfam16381
      Location:756 → 871
      Coatomer_g_Cpla; Coatomer subunit gamma-1 C-terminal appendage platform
      sd00044
      Location:395 → 420
      HEAT; HEAT repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q22498.1

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