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    HLR1 Hlr1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852141, updated on 2-Nov-2024

    Summary

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    Official Symbol
    HLR1
    Official Full Name
    Hlr1p
    Primary source
    SGD:S000002936
    Locus tag
    YDR528W
    See related
    AllianceGenome:SGD:S000002936; FungiDB:YDR528W; VEuPathDB:YDR528W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in fungal-type cell wall organization. Located in cytoplasm. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See HLR1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (1494586..1495857)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Rba50p Neighboring gene ncRNA Neighboring gene ubiquinol--cytochrome-c reductase subunit 7 Neighboring gene bifunctional AP-4-A phosphorylase/ADP sulfurylase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Hyperosmotic stress response and regulation of cell wall integrity in Saccharomyces cerevisiae share common functional aspects. Alonso-Monge R, et al. Mol Microbiol, 2001 Aug. PMID 11532139
    2. Lre1 affects chitinase expression, trehalose accumulation and heat resistance through inhibition of the Cbk1 protein kinase in Saccharomyces cerevisiae. Versele M, et al. Mol Microbiol, 2001 Sep. PMID 11580836
    3. A constraint network of interactions: protein-protein interaction analysis of the yeast type II phosphatase Ptc1p and its adaptor protein Nbp2p. Hruby A, et al. J Cell Sci, 2011 Jan 1. PMID 21118957
    4. Whi3, an S. cerevisiae RNA-binding protein, is a component of stress granules that regulates levels of its target mRNAs. Holmes KJ, et al. PLoS One, 2013. PMID 24386330, Free PMC Article
    5. Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein. Willingham S, et al. Science, 2003 Dec 5. PMID 14657499

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell wall organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in fungal-type cell wall organization IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Hlr1p
    NP_010817.3
    • Protein involved in regulation of cell wall composition and integrity; also involved in cell wall response to osmotic stress; overproduction suppresses a lysis sensitive PKC mutation; HLR1 has a paralog, LRE1, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      1494586..1495857
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180836.3 → NP_010817.3  TPA: Hlr1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010817.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VTE9, Q04429
      UniProtKB/TrEMBL
      N1P7K5
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q04429.1

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