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    TDA9 Tda9p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854894, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TDA9
    Official Full Name
    Tda9p
    Primary source
    SGD:S000004546
    Locus tag
    YML081W
    See related
    AllianceGenome:SGD:S000004546; FungiDB:YML081W; VEuPathDB:YML081W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    AAF1
    Summary
    Enables sequence-specific DNA binding activity. Involved in acetate biosynthetic process. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See TDA9 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (104777..108532)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene putative cystathionine gamma-synthase Neighboring gene F1F0 ATP synthase subunit i Neighboring gene tRNA dihydrouridine synthase Neighboring gene Cff1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Linking DNA-binding proteins to their recognition sequences by using protein microarrays. Ho SW, et al. Proc Natl Acad Sci U S A, 2006 Jun 27. PMID 16785442, Free PMC Article
    2. Functional improvement of Saccharomyces cerevisiae to reduce volatile acidity in wine. Luo Z, et al. FEMS Yeast Res, 2013 Aug. PMID 23692528
    3. The fermentation stress response protein Aaf1p/Yml081Wp regulates acetate production in Saccharomyces cerevisiae. Walkey CJ, et al. PLoS One, 2012. PMID 23240040, Free PMC Article
    4. Diversification of transcription factor paralogs via noncanonical modularity in C2H2 zinc finger DNA binding. Siggers T, et al. Mol Cell, 2014 Aug 21. PMID 25042805, Free PMC Article
    5. Identifying cooperative transcription factors by combining ChIP-chip data and knockout data. Yang Y, et al. Cell Res, 2010 Nov. PMID 20975739

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding HDA PubMed 
    enables sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables zinc ion binding RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in acetate biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Tda9p
    NP_013630.1
    • Transcription factor that regulates acetate production; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene; TDA9 has a paralog, RSF2, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      104777..108532
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182440.1 → NP_013630.1  TPA: Tda9p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013630.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W0K2, Q03621, Q04545
      UniProtKB/TrEMBL
      N1P653
      Conserved Domains (3) summary
      cd12148
      Location:665 → 783
      fungal_TF_MHR; fungal transcription factor regulatory middle homology region
      COG5048
      Location:29 → 235
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:63 → 83
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q04545.1

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