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    yak3 aldose reductase ARK13 family YakC, implicated in cellular detoxification from family members [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541648, updated on 18-Sep-2024

    Summary

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    Official Symbol
    yak3
    Official Full Name
    aldose reductase ARK13 family YakC, implicated in cellular detoxification from family members
    Primary source
    PomBase:SPAC1F7.12
    Locus tag
    SPOM_SPAC1F7.12
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    SPAC21E11.01; yakC
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    Genomic context

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    See yak3 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (4248932..4250231)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene transcription factor Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 60S ribosomal protein uL2 Neighboring gene ncRNA Neighboring gene DNA-binding transcription factor Pcr1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of recombinant YakC of Schizosaccharomyces pombe showing YakC defines a new family of aldo-keto reductases. Morita T, et al. J Biochem, 2002 Oct. PMID 12359080
    2. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
    3. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article
    4. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360
    5. The mitochondrial genome of the fission yeast Schizosaccharomyces pombe: highly homologous introns are inserted at the same position of the otherwise less conserved cox1 genes in Schizosaccharomyces pombe and Aspergillus nidulans. Lang BF. EMBO J, 1984 Sep. PMID 6092057, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables aldo-keto reductase (NADPH) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxidoreductase activity, acting on CH-OH group of donors IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    NOT enables pyridoxal 4-dehydrogenase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    aldose reductase ARK13 family YakC, implicated in cellular detoxification from family members

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4248932..4250231
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019927.3 → NP_594498.1  aldose reductase ARK13 family YakC, implicated in cellular detoxification from family members [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594498.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q09923
      Conserved Domains (2) summary
      cd06660
      Location:5 → 312
      Aldo_ket_red; Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial ...
      COG0667
      Location:3 → 320
      Tas; Predicted oxidoreductase (related to aryl-alcohol dehydrogenase) [General function prediction only]
    Nucleotide Protein
    Heading Accession and Version

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