U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    mto2 gamma tubulin complex linker Mto2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541264, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    mto2
    Official Full Name
    gamma tubulin complex linker Mto2
    Primary source
    PomBase:SPBC902.06
    Locus tag
    SPOM_SPBC902.06
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See mto2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003423.3 (494679..496423)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene MTREC (exosome adaptor) complex RNA-binding subunit Rmn1 Neighboring gene ncRNA Neighboring gene isocitrate dehydrogenase (NAD+) subunit 2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene dual-specificity MAP kinase phosphatase Pmp1 Neighboring gene 40S ribosomal protein eS12

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Two distinct regions of Mto1 are required for normal microtubule nucleation and efficient association with the gamma-tubulin complex in vivo. Samejima I, et al. J Cell Sci, 2008 Dec 1. PMID 19001497, Free PMC Article
    2. Mto2p, a novel fission yeast protein required for cytoplasmic microtubule organization and anchoring of the cytokinetic actin ring. Venkatram S, et al. Mol Biol Cell, 2005 Jun. PMID 15800064, Free PMC Article
    3. Mto2 multisite phosphorylation inactivates non-spindle microtubule nucleation complexes during mitosis. Borek WE, et al. Nat Commun, 2015 Aug 5. PMID 26243668, Free PMC Article
    4. Activation of the γ-tubulin complex by the Mto1/2 complex. Lynch EM, et al. Curr Biol, 2014 Apr 14. PMID 24704079, Free PMC Article
    5. Efficient formation of bipolar microtubule bundles requires microtubule-bound gamma-tubulin complexes. Janson ME, et al. J Cell Biol, 2005 Apr 25. PMID 15837798, Free PMC Article

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Mto1/2 complex disassembles during mitosis, coincident with hyperphosphorylation of Mto2 protein
      Title: Mto2 multisite phosphorylation inactivates non-spindle microtubule nucleation complexes during mitosis.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    contributes_to cytoskeletal protein-membrane anchor activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in interphase microtubule organizing center assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in microtubule bundle formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mitotic cytokinesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in nuclear migration IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cell division site HDA PubMed 
    is_active_in cytoplasm HDA PubMed 
    is_active_in cytoplasmic microtubule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in equatorial microtubule organizing center IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in interphase microtubule organizing center IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in microtubule cytoskeleton IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in mitotic spindle pole body HDA PubMed 
    is_active_in mitotic spindle pole body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in static microtubule bundle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    gamma tubulin complex linker Mto2

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      494679..496423
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001355846.2 → NP_001342930.1  gamma tubulin complex linker Mto2 [Schizosaccharomyces pombe]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9USP7, Q9UTV6
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials