U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    mst1 histone acetyltransferase, KAT5 family Mst1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543506, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    mst1
    Official Full Name
    histone acetyltransferase, KAT5 family Mst1
    Primary source
    PomBase:SPAC637.12c
    Locus tag
    SPOM_SPAC637.12C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    kat5
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See mst1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (4559101..4562829, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene putative ribonuclease H70 Neighboring gene ncRNA Neighboring gene 19S proteasome regulatory subunit Rpn10 Neighboring gene ATP-dependent RNA helicase Rpm2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene cytoskeletal signaling protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Chromodomain mutation in S. pombe Kat5/Mst1 affects centromere dynamics and DNA repair. Li T, et al. PLoS One, 2024. PMID 38662722, Free PMC Article
    2. Schizosaccharomyces pombe KAT5 contributes to resection and repair of a DNA double-strand break. Li T, et al. Genetics, 2021 May 17. PMID 33723569, Free PMC Article
    3. The fission yeast inhibitor of growth (ING) protein Png1p functions in response to DNA damage. Chen JQ, et al. J Biol Chem, 2010 May 21. PMID 20299455, Free PMC Article
    4. BAF53/Arp4 homolog Alp5 in fission yeast is required for histone H4 acetylation, kinetochore-spindle attachment, and gene silencing at centromere. Minoda A, et al. Mol Biol Cell, 2005 Jan. PMID 15483052, Free PMC Article
    5. The NuA4 acetyltransferase and histone H4 acetylation promote replication recovery after topoisomerase I-poisoning. Noguchi C, et al. Epigenetics Chromatin, 2019 Apr 16. PMID 30992049, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Chromodomain mutation in S. pombe Kat5/Mst1 affects centromere dynamics and DNA repair.
      Title: Chromodomain mutation in S. pombe Kat5/Mst1 affects centromere dynamics and DNA repair.
    2. Mst1 plays essential roles in maintenance of genome stability and recovery from DNA damage.
      Title: Schizosaccharomyces pombe histone acetyltransferase Mst1 (KAT5) is an essential protein required for damage response and chromosome segregation.
    Submit: New GeneRIF Correction

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables histone H3K4 acetyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables histone H4K16 acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables peptide 2-hydroxyisobutyryltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables peptide N-acetyltransferase activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables peptide butyryltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables peptide crotonyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription coregulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA repair-dependent chromatin remodeling IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of heterochromatin formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of NuA4 histone acetyltransferase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of NuA4 histone acetyltransferase complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of Swr1 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in pericentric heterochromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in site of double-strand break IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    histone acetyltransferase, KAT5 family Mst1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4559101..4562829 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020058.3 → NP_594630.1  histone acetyltransferase, KAT5 family Mst1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594630.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O94446, Q9USC8
      Conserved Domains (3) summary
      COG5027
      Location:16 → 447
      SAS2; Histone acetyltransferase (MYST family) [Chromatin structure and dynamics]
      pfam11717
      Location:21 → 74
      Tudor-knot; RNA binding activity-knot of a chromodomain
      cl17182
      Location:176 → 451
      NAT_SF; N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.