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    abc3 multi drug resistance-associated protein abc3 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540937, updated on 18-Sep-2024

    Summary

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    Official Symbol
    abc3
    Official Full Name
    multi drug resistance-associated protein abc3
    Primary source
    PomBase:SPBC359.05
    Locus tag
    SPOM_SPBC359.05
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See abc3 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (122642..127461)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene adducin, involved in actin cytoskeleton organization

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Heme Assimilation in Schizosaccharomyces pombe Requires Cell-surface-anchored Protein Shu1 and Vacuolar Transporter Abc3. Mourer T, et al. J Biol Chem, 2017 Mar 24. PMID 28193844, Free PMC Article
    2. The major facilitator transporter Str3 is required for low-affinity heme acquisition in Schizosaccharomyces pombe. Normant V, et al. J Biol Chem, 2018 Apr 27. PMID 29549126, Free PMC Article
    3. abc3+ encodes an iron-regulated vacuolar ABC-type transporter in Schizosaccharomyces pombe. Pouliot B, et al. Eukaryot Cell, 2010 Jan. PMID 19915076, Free PMC Article
    4. A survey of all 11 ABC transporters in fission yeast: two novel ABC transporters are required for red pigment accumulation in a Schizosaccharomyces pombe adenine biosynthetic mutant. Iwaki T, et al. Microbiology (Reading), 2006 Aug. PMID 16849797
    5. The PAF complex and Prf1/Rtf1 delineate distinct Cdk9-dependent pathways regulating transcription elongation in fission yeast. Mbogning J, et al. PLoS Genet, 2013. PMID 24385927, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ABC-type heme transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATPase-coupled transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables heme binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in heme export from vacuole to cytoplasm IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in fungal-type vacuole IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in fungal-type vacuole membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    multi drug resistance-associated protein abc3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      122642..127461
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020961.3 → NP_595055.1  multi drug resistance-associated protein abc3 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595055.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9P5N0, Q9UU44
    Nucleotide Protein
    Heading Accession and Version

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