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    glt1 glutamate synthase Glt1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543509, updated on 18-Sep-2024

    Summary

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    Official Symbol
    glt1
    Official Full Name
    glutamate synthase Glt1
    Primary source
    PomBase:SPAPB1E7.07
    Locus tag
    SPOM_SPAPB1E7.07
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    glu4; gog1
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    Genomic context

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    See glt1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (3302825..3310369)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene transporter Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein O-mannosyltransferase Ogm2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Presence of glutamate synthase in fission yeasts and its possible role in ammonia assimilation. Brown CM, et al. Nat New Biol, 1973 Nov 28. PMID 4148397
    2. Glutamine synthetase/glutamate synthase ammonium-assimilating pathway in Schizosaccharomyces pombe. Perysinakis A, et al. Curr Microbiol, 1995 Jun. PMID 7773104
    3. Enzyme defects in glutamate-requiring strains of Schizosaccharomyces pombe. Barel I, et al. FEMS Microbiol Lett, 1993 Nov 1. PMID 7903653
    4. Filamentous invasive growth of mutants of the genes encoding ammonia-metabolizing enzymes in the fission yeast Schizosaccharomyces pombe. Sasaki Y, et al. PLoS One, 2017. PMID 28982178, Free PMC Article
    5. A Two-step Protein Quality Control Pathway for a Misfolded DJ-1 Variant in Fission Yeast. Mathiassen SG, et al. J Biol Chem, 2015 Aug 21. PMID 26152728, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables 3 iron, 4 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables FMN binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables flavin adenine dinucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glutamate synthase (NADH) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glutamate synthase (NADH) activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in L-glutamate biosynthetic process EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in L-glutamate biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in ammonia assimilation cycle EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in ammonia assimilation cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ammonia assimilation cycle IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in glutamate biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    is_active_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    glutamate synthase Glt1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      3302825..3310369
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019557.3 → NP_594133.1  glutamate synthase Glt1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594133.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P78816, Q9C102
      Conserved Domains (8) summary
      TIGR01317
      Location:1613 → 2099
      GOGAT_sm_gam; glutamate synthases, NADH/NADPH, small subunit
      PRK11750
      Location:56 → 1567
      gltB; glutamate synthase subunit alpha; Provisional
      cd00982
      Location:1303 → 1552
      gltB_C; gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the ...
      cd02808
      Location:880 → 1260
      GltS_FMN; Glutamate synthase (GltS) FMN-binding domain. GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast ...
      pfam00310
      Location:69 → 492
      GATase_2; Glutamine amidotransferases class-II
      pfam04898
      Location:528 → 815
      Glu_syn_central; Glutamate synthase central domain
      pfam13450
      Location:1760 → 1804
      NAD_binding_8; NAD(P)-binding Rossmann-like domain
      cl19102
      Location:1635 → 1744
      Fer4_8; 4Fe-4S dicluster domain
    Nucleotide Protein
    Heading Accession and Version

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