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    cbf5 pseudouridylate synthase Cbf5 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542481, updated on 18-Sep-2024

    Summary

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    Official Symbol
    cbf5
    Official Full Name
    pseudouridylate synthase Cbf5
    Primary source
    PomBase:SPAC29A4.04c
    Locus tag
    SPOM_SPAC29A4.04C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See cbf5 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (5140340..5142190)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene myosin I light chain Cam2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Schizosaccharomyces specific protein Neighboring gene ncRNA Neighboring gene putative mitochondrial ribosomal protein subunit Mrps9 Neighboring gene translation elongation factor EF-1 gamma subunit Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Nrd1-like protein Seb1 coordinates cotranscriptional 3' end processing and polyadenylation site selection. Lemay JF, et al. Genes Dev, 2016 Jul 1. PMID 27401558, Free PMC Article
    2. Poly(A) tail-mediated gene regulation by opposing roles of Nab2 and Pab2 nuclear poly(A)-binding proteins in pre-mRNA decay. Grenier St-Sauveur V, et al. Mol Cell Biol, 2013 Dec. PMID 24081329, Free PMC Article
    3. Proteome-wide search for PP2A substrates in fission yeast. Bernal M, et al. Proteomics, 2014 Jun. PMID 24634168
    4. Transcription and chromatin-based surveillance mechanism controls suppression of cryptic antisense transcription. Heo DH, et al. Cell Rep, 2021 Sep 7. PMID 34496258, Free PMC Article
    5. Proteomic profiling and functional characterization of post-translational modifications of the fission yeast RNA exosome. Telekawa C, et al. Nucleic Acids Res, 2018 Nov 30. PMID 30321377, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables box H/ACA snoRNA binding IC
    Inferred by Curator
    more info
    		  
    enables pseudouridine synthase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables rRNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables snRNA pseudouridine synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in box H/ACA sno(s)RNA 3'-end processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mRNA pseudouridine synthesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in rRNA pseudouridine synthesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in snRNA pseudouridine synthesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of box H/ACA snoRNP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 

    General protein information

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    Preferred Names
    pseudouridylate synthase Cbf5

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      5140340..5142190
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020307.3 → NP_594878.1  pseudouridylate synthase Cbf5 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594878.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O14007
      Conserved Domains (4) summary
      cd02572
      Location:63 → 245
      PseudoU_synth_hDyskerin; Pseudouridine synthase, human dyskerin like
      TIGR00425
      Location:31 → 356
      CBF5; rRNA pseudouridine synthase, putative
      pfam01472
      Location:272 → 345
      PUA; PUA domain
      pfam08068
      Location:24 → 81
      DKCLD; DKCLD (NUC011) domain
    Nucleotide Protein
    Heading Accession and Version

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