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    bir1 survivin Bir1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2538875, updated on 18-Sep-2024

    Summary

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    Official Symbol
    bir1
    Official Full Name
    survivin Bir1
    Primary source
    PomBase:SPCC962.02c
    Locus tag
    SPOM_SPCC962.02C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    cut17; pbh1; SPCP31B10.10c
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    Genomic context

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    See bir1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    2
    Sequence:
    Chromosome: III; NC_003421.2 (545805..549299, complement)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene tricalbin, C2 domain protein (phospholipid binding) ER-plasma membrane tethering protein Tcb1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene importin alpha family nuclear import signal receptor adaptor Cut15 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Schizosaccharomyces pombe homolog of Survivin, Bir1p, exhibits a novel dynamic behavior at the spindle mid-zone. Rajagopalan S, et al. Genes Cells, 2006 Jul. PMID 16824200
    2. Role for yeast inhibitor of apoptosis (IAP)-like proteins in cell division. Uren AG, et al. Proc Natl Acad Sci U S A, 1999 Aug 31. PMID 10468581, Free PMC Article
    3. Bir1/Cut17 moving from chromosome to spindle upon the loss of cohesion is required for condensation, spindle elongation and repair. Morishita J, et al. Genes Cells, 2001 Sep. PMID 11554922
    4. Schizosaccharomyces pombe Bir1p, a nuclear protein that localizes to kinetochores and the spindle midzone, is essential for chromosome condensation and spindle elongation during mitosis. Rajagopalan S, et al. Genetics, 2002 Feb. PMID 11861551, Free PMC Article
    5. Suppressors of Bir1p (Survivin) identify roles for the chromosomal passenger protein Pic1p (INCENP) and the replication initiation factor Psf2p in chromosome segregation. Huang HK, et al. Mol Cell Biol, 2005 Oct. PMID 16199877, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitotic sister chromatid biorientation EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in mitotic sister chromatid biorientation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mitotic sister chromatid segregation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of mitotic cytokinesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in signaling NAS
    Non-traceable Author Statement
    more info
    		  
    Component Evidence Code Pubs
    is_active_in chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of chromosome passenger complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in kinetochore IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in meiotic spindle midzone IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in mitotic spindle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in mitotic spindle midzone IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in pericentric heterochromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    survivin Bir1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      545805..549299 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022859.4 → NP_587866.3  survivin Bir1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_587866.3

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O14064, Q9USG4, Q9UTZ0
      Conserved Domains (2) summary
      smart00238
      Location:21 → 100
      BIR; Baculoviral inhibition of apoptosis protein repeat
      pfam00653
      Location:120 → 194
      BIR; Inhibitor of Apoptosis domain
    Nucleotide Protein
    Heading Accession and Version

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