U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    rpn10 19S proteasome regulatory subunit Rpn10 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543682, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    rpn10
    Official Full Name
    19S proteasome regulatory subunit Rpn10
    Primary source
    PomBase:SPAC637.10c
    Locus tag
    SPOM_SPAC637.10C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    pus1
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See rpn10 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    4
    Sequence:
    Chromosome: I; NC_003424.3 (4557551..4558696, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Fe-sulfur cluster assembly ATPase Nbp35 Neighboring gene putative ribonuclease H70 Neighboring gene ncRNA Neighboring gene ATP-dependent RNA helicase Rpm2 Neighboring gene histone acetyltransferase, KAT5 family Mst1 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Structure of Rpn10 and its interactions with polyubiquitin chains and the proteasome subunit Rpn12. Riedinger C, et al. J Biol Chem, 2010 Oct 29. PMID 20739285, Free PMC Article
    2. Analysis of a gene encoding Rpn10 of the fission yeast proteasome reveals that the polyubiquitin-binding site of this subunit is essential when Rpn12/Mts3 activity is compromised. Wilkinson CR, et al. J Biol Chem, 2000 May 19. PMID 10809753
    3. The Ubx2 and Ubx3 cofactors direct Cdc48 activity to proteolytic and nonproteolytic ubiquitin-dependent processes. Hartmann-Petersen R, et al. Curr Biol, 2004 May 4. PMID 15120077
    4. Structural and functional characterization of Rpn12 identifies residues required for Rpn10 proteasome incorporation. Boehringer J, et al. Biochem J, 2012 Nov 15. PMID 22906049, Free PMC Article
    5. Interaction of the anaphase-promoting complex/cyclosome and proteasome protein complexes with multiubiquitin chain-binding proteins. Seeger M, et al. J Biol Chem, 2003 May 9. PMID 12615927

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. SpRpn12 could modulate the activity of SpRpn10 as a proteasomal Ub receptor
      Title: Structure of Rpn10 and its interactions with polyubiquitin chains and the proteasome subunit Rpn12.
    Submit: New GeneRIF Correction

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables K48-linked polyubiquitin modification-dependent protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitotic recombination-dependent replication fork processing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IC
    Inferred by Curator
    more info
    		  
    involved_in stalled replication fork localization to nuclear periphery IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 
    part_of proteasome regulatory particle, base subcomplex IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    part_of proteasome regulatory particle, lid subcomplex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    19S proteasome regulatory subunit Rpn10

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4557551..4558696 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020056.3 → NP_594628.1  19S proteasome regulatory subunit Rpn10 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594628.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O94444
      Conserved Domains (1) summary
      COG5148
      Location:1 → 243
      RPN10; 26S proteasome regulatory complex, subunit RPN10/PSMD4 [Posttranslational modification, protein turnover, chaperones]
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials