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    thp1 uracil DNA N-glycosylase Thp1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539432, updated on 18-Sep-2024

    Summary

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    Official Symbol
    thp1
    Official Full Name
    uracil DNA N-glycosylase Thp1
    Primary source
    PomBase:SPCC965.05c
    Locus tag
    SPOM_SPCC965.05C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See thp1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_003421.2 (2290888..2292139, complement)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene V-type ATPase V1 subunit D Neighboring gene i-AAA protease Yme1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene potassium channel subunit Neighboring gene glutathione S-transferase Gst2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Repair of deaminated base damage by Schizosaccharomyces pombe thymine DNA glycosylase. Dong L, et al. DNA Repair (Amst), 2008 Dec 1. PMID 18789404
    2. The versatile thymine DNA-glycosylase: a comparative characterization of the human, Drosophila and fission yeast orthologs. Hardeland U, et al. Nucleic Acids Res, 2003 May 1. PMID 12711670, Free PMC Article
    3. Nucleocytoplasmic transport in the midzone membrane domain controls yeast mitotic spindle disassembly. Lucena R, et al. J Cell Biol, 2015 May 11. PMID 25963819, Free PMC Article
    4. The fission yeast nucleoporin Alm1 is required for proteasomal degradation of kinetochore components. Salas-Pino S, et al. J Cell Biol, 2017 Nov 6. PMID 28974540, Free PMC Article
    5. Predicting the fission yeast protein interaction network. Pancaldi V, et al. G3 (Bethesda), 2012 Apr. PMID 22540037, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables G/U mismatch-specific uracil-DNA glycosylase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hypoxanthine DNA N-glycosylase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables oxanine DNA N-glycosylase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables pyrimidine-specific mismatch base pair DNA N-glycosylase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables uracil DNA N-glycosylase activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables uracil DNA N-glycosylase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables uracil DNA N-glycosylase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables xanthine DNA N-glycosylase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in base-excision repair, AP site formation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    uracil DNA N-glycosylase Thp1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      2290888..2292139 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023504.3 → NP_588515.1  uracil DNA N-glycosylase Thp1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_588515.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O59825
      Conserved Domains (1) summary
      cl00483
      Location:5 → 325
      UDG_like; Uracil-DNA glycosylases (UDG) and related enzymes
    Nucleotide Protein
    Heading Accession and Version

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