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    duf89 cobalt/nickel-dependent phosphatase [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2538830, updated on 18-Sep-2024

    Summary

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    Official Symbol
    duf89
    Official Full Name
    cobalt/nickel-dependent phosphatase
    Primary source
    PomBase:SPCC1393.13
    Locus tag
    SPOM_SPCC1393.13
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    prl64
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    Genomic context

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    See duf89 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    2
    Sequence:
    Chromosome: III; NC_003421.2 (824998..827652)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene mitochondrial 54S ribosomal protein mL58 Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene inorganic phosphate transporter

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Fission yeast Duf89 and Duf8901 are cobalt/nickel-dependent phosphatase-pyrophosphatases that act via a covalent aspartyl-phosphate intermediate. Sanchez AM, et al. J Biol Chem, 2022 May. PMID 35314193, Free PMC Article
    2. Systematic screen of Schizosaccharomyces pombe deletion collection uncovers parallel evolution of the phosphate signal transduction pathway in yeasts. Henry TC, et al. Eukaryot Cell, 2011 Feb. PMID 21169418, Free PMC Article
    3. A family of metal-dependent phosphatases implicated in metabolite damage-control. Huang L, et al. Nat Chem Biol, 2016 Aug. PMID 27322068, Free PMC Article
    4. A central role for TOR signalling in a yeast model for juvenile CLN3 disease. Bond ME, et al. Microb Cell, 2015 Nov 11. PMID 28357272, Free PMC Article
    5. Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. Stewart EV, et al. Mol Cell, 2011 Apr 22. PMID 21504829, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables fructose 6-phosphate aldolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables fructose-1-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables inorganic diphosphate phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables metal ion binding EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA damage response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cellular detoxification ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    involved_in intracellular phosphate ion homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    cobalt/nickel-dependent phosphatase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      824998..827652
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022962.3 → NP_587971.1  cobalt/nickel-dependent phosphatase [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_587971.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O94725
      Conserved Domains (1) summary
      pfam01937
      Location:25 → 420
      DUF89; Protein of unknown function DUF89
    Nucleotide Protein
    Heading Accession and Version

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