U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    bop1 ubiquitin-protein ligase E3 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542072, updated on 22-Jun-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    bop1
    Gene description
    ubiquitin-protein ligase E3
    Locus tag
    SPOM_SPAP32A8.03C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Old locus tag
    SPAP32A8.03c
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See bop1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (3407545..3409604, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene anaphase-promoting complex platform subcomplex scaffold TPR subunit Apc5 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene xylose and arabinose reductase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 60S ribosomal protein uL18

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Dsc E3 ligase localization to the Golgi requires the ATPase Cdc48 and cofactor Ufd1 for activation of sterol regulatory element-binding protein in fission yeast. Burr R, et al. J Biol Chem, 2017 Sep 29. PMID 28821619, Free PMC Article
    2. Large scale screening of genetic interaction with sgf73(+) in fission yeast. Guo Y, et al. Yi Chuan, 2014 Jul. PMID 25076038
    3. Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast. Roguev A, et al. Science, 2008 Oct 17. PMID 18818364, Free PMC Article
    4. Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. Stewart EV, et al. Mol Cell, 2011 Apr 22. PMID 21504829, Free PMC Article
    5. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables zinc ion binding ISM
    Inferred from Sequence Model
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    ubiquitin-protein ligase E3

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      3407545..3409604 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019603.3 → NP_594179.1  ubiquitin-protein ligase E3 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594179.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9C1X4
      Conserved Domains (3) summary
      COG5243
      Location:379 → 501
      HRD1; HRD ubiquitin ligase complex, ER membrane component [Posttranslational modification, protein turnover, chaperones]
      cd16454
      Location:395 → 437
      RING-H2_PA-TM-RING; RING finger, H2 subclass, found in the PA-TM-RING ubiquitin ligase family
      cl19201
      Location:1 → 34
      HypA; Hydrogenase/urease nickel incorporation, metallochaperone, hypA
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials