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    rhp41 DNA repair protein Rhp41 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542967, updated on 18-Sep-2024

    Summary

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    Official Symbol
    rhp41
    Official Full Name
    DNA repair protein Rhp41
    Primary source
    PomBase:SPAC12B10.12c
    Locus tag
    SPOM_SPAC12B10.12C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    rhp4a
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    Genomic context

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    See rhp41 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (4593600..4596095, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein Nod1 Neighboring gene glucan glucosidase exg2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ubiquitin ligase complex subunit protein Neighboring gene serine/threonine protein kinase Ppk2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Two budding yeast RAD4 homologs in fission yeast play different roles in the repair of UV-induced DNA damage. Fukumoto Y, et al. DNA Repair (Amst), 2002 Oct 1. PMID 12531030
    2. Fission yeast homologs of human XPC and CSB, rhp41 and rhp26, are involved in transcription-coupled repair of methyl methanesulfonate-induced DNA damage. Kanamitsu K, et al. Genes Genet Syst, 2011. PMID 21670547
    3. Repair of damaged and mismatched DNA by the XPC homologues Rhp41 and Rhp42 of fission yeast. Marti TM, et al. Genetics, 2003 Jun. PMID 12807767, Free PMC Article
    4. Brc1-mediated rescue of Smc5/6 deficiency: requirement for multiple nucleases and a novel Rad18 function. Lee KM, et al. Genetics, 2007 Apr. PMID 17277362, Free PMC Article
    5. Nsk1 ensures accurate chromosome segregation by promoting association of kinetochores to spindle poles during anaphase B. Buttrick GJ, et al. Mol Biol Cell, 2011 Dec. PMID 21965289, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Fission yeast homologs of human XPC and CSB, rhp41 and rhp26, are involved in transcription-coupled repair of methyl methanesulfonate-induced DNA damage.
      Title: Fission yeast homologs of human XPC and CSB, rhp41 and rhp26, are involved in transcription-coupled repair of methyl methanesulfonate-induced DNA damage.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables damaged DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables single-stranded DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in mismatch repair IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mismatch repair IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in nucleotide-excision repair IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in nucleotide-excision repair IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of XPC complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in mitotic spindle HDA PubMed 
    part_of nucleotide-excision repair factor 2 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    DNA repair protein Rhp41

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4593600..4596095 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020072.3 → NP_594644.1  DNA repair protein Rhp41 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594644.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q10445
      Conserved Domains (5) summary
      smart01031
      Location:472 → 515
      BHD_2; Rad4 beta-hairpin domain 2
      TIGR00605
      Location:1 → 638
      rad4; DNA repair protein rad4
      pfam03835
      Location:269 → 412
      Rad4; Rad4 transglutaminase-like domain
      pfam10403
      Location:417 → 469
      BHD_1; Rad4 beta-hairpin domain 1
      pfam10405
      Location:523 → 593
      BHD_3; Rad4 beta-hairpin domain 3
    Nucleotide Protein
    Heading Accession and Version

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