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    egt1 ergothioneine biosynthesis protein Egt1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539656, updated on 18-Sep-2024

    Summary

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    Official Symbol
    egt1
    Official Full Name
    ergothioneine biosynthesis protein Egt1
    Primary source
    PomBase:SPBC1604.01
    Locus tag
    SPOM_SPBC1604.01
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    mug158; SPBC1677.01c
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    Genomic context

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    See egt1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (3930495..3933264, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene PPR repeat-containing protein Ppr1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and metabolomic dissection of the ergothioneine and selenoneine biosynthetic pathway in the fission yeast, S. pombe, and construction of an overproduction system. Pluskal T, et al. PLoS One, 2014. PMID 24828577, Free PMC Article
    2. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
    3. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article
    4. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360
    5. The mitochondrial genome of the fission yeast Schizosaccharomyces pombe: highly homologous introns are inserted at the same position of the otherwise less conserved cox1 genes in Schizosaccharomyces pombe and Aspergillus nidulans. Lang BF. EMBO J, 1984 Sep. PMID 6092057, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables L-histidine N(alpha)-methyltransferase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables calcium ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables hercynylcysteine sulfoxide synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in ergothioneine biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in selenoneine biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    ergothioneine biosynthesis protein Egt1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3930495..3933264 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022560.4 → NP_596639.2  ergothioneine biosynthesis protein Egt1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596639.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O94367, O94632, Q1MTP5
      Conserved Domains (5) summary
      COG1262
      Location:435 → 773
      YfmG; Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain [Posttranslational modification, protein turnover, chaperones]
      COG4301
      Location:19 → 320
      COG4301; Uncharacterized conserved protein, contains predicted SAM-dependent methyltransferase domain [General function prediction only]
      pfam03781
      Location:560 → 772
      FGE-sulfatase; Sulfatase-modifying factor enzyme 1
      pfam10017
      Location:199 → 320
      Methyltransf_33; Histidine-specific methyltransferase, SAM-dependent
      pfam13649
      Location:81 → 192
      Methyltransf_25; Methyltransferase domain
    Nucleotide Protein
    Heading Accession and Version

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