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    pct1 RNA 5'-triphosphatase [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543671, updated on 18-Sep-2024

    Summary

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    Official Symbol
    pct1
    Official Full Name
    RNA 5'-triphosphatase
    Primary source
    PomBase:SPAC644.04
    Locus tag
    SPOM_SPAC644.04
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See pct1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (2677086..2679291)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ESCRT III complex subunit Did4 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene deoxyuridine 5'-triphosphate nucleotidohydrolase Neighboring gene serine/threonine protein kinase (NIM1 family) Cdr1/Nim1 Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of Schizosaccharomyces pombe RNA triphosphatase. Pei Y, et al. Nucleic Acids Res, 2001 Jan 15. PMID 11139608, Free PMC Article
    2. Homodimeric quaternary structure is required for the in vivo function and thermal stability of Saccharomyces cerevisiae and Schizosaccharomyces pombe RNA triphosphatases. Hausmann S, et al. J Biol Chem, 2003 Aug 15. PMID 12788946
    3. The length, phosphorylation state, and primary structure of the RNA polymerase II carboxyl-terminal domain dictate interactions with mRNA capping enzymes. Pei Y, et al. J Biol Chem, 2001 Jul 27. PMID 11387325
    4. Fission yeast RNA triphosphatase reads an Spt5 CTD code. Doamekpor SK, et al. RNA, 2015 Jan. PMID 25414009, Free PMC Article
    5. Interactions between fission yeast Cdk9, its cyclin partner Pch1, and mRNA capping enzyme Pct1 suggest an elongation checkpoint for mRNA quality control. Pei Y, et al. J Biol Chem, 2003 Feb 28. PMID 12475973

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Pct1 binding to Spt5 CTD is antagonized by threonine phosphorylation.
      Title: Fission yeast RNA triphosphatase reads an Spt5 CTD code.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP hydrolysis activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables RNA polymerase II C-terminal domain binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables mRNA 5'-triphosphate monophosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables polynucleotide 5'-phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables polynucleotide 5'-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in 7-methylguanosine mRNA capping IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in 7-methylguanosine mRNA capping IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    NOT part_of mRNA capping enzyme complex EXP
    Inferred from Experiment
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    RNA 5'-triphosphatase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      2677086..2679291
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019302.3 → NP_593872.1  RNA 5'-triphosphatase [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593872.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9P6Q6
      Conserved Domains (1) summary
      pfam02940
      Location:55 → 263
      mRNA_triPase; mRNA capping enzyme, beta chain
    Nucleotide Protein
    Heading Accession and Version

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    Research Materials