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    fps1 geranyltranstransferase Fps1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542898, updated on 18-Sep-2024

    Summary

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    Official Symbol
    fps1
    Official Full Name
    geranyltranstransferase Fps1
    Primary source
    PomBase:SPAC6F12.13c
    Locus tag
    SPOM_SPAC6F12.13C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See fps1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (1338365..1339932, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene transcription factor TFIIIC subunit Sfc1 Neighboring gene ncRNA Neighboring gene serine/threonine protein phosphatase PP2A regulatory subunit B-56 Par2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene anaphase-promoting complex TPR lobe subcomplex subunit Apc8 Neighboring gene ncRNA Neighboring gene anaphase-promoting complex TPR lobe subcomplex subunit Cut9/Apc6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Geranylgeranyl diphosphate synthase in fission yeast is a heteromer of farnesyl diphosphate synthase (FPS), Fps1, and an FPS-like protein, Spo9, essential for sporulation. Ye Y, et al. Mol Biol Cell, 2007 Sep. PMID 17596513, Free PMC Article
    2. Dual recruitment of Cdc48 (p97)-Ufd1-Npl4 ubiquitin-selective segregase by small ubiquitin-like modifier protein (SUMO) and ubiquitin in SUMO-targeted ubiquitin ligase-mediated genome stability functions. Nie M, et al. J Biol Chem, 2012 Aug 24. PMID 22730331, Free PMC Article
    3. Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. Ren L, et al. PLoS One, 2011 Feb 28. PMID 21386897, Free PMC Article
    4. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article
    5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables dimethylallyltranstransferase activity ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    contributes_to farnesyltranstransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables geranyltranstransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables geranyltranstransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ergosterol biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    involved_in farnesyl diphosphate biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in farnesyl diphosphate biosynthetic process, mevalonate pathway EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in geranyl diphosphate biosynthetic process IC
    Inferred by Curator
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    geranyltranstransferase Fps1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      1338365..1339932 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018729.3 → NP_593299.1  geranyltranstransferase Fps1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593299.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O14230, P78756
      Conserved Domains (1) summary
      pfam00348
      Location:44 → 304
      polyprenyl_synt; Polyprenyl synthetase
    Nucleotide Protein
    Heading Accession and Version

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