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    stc1 CLRC complex-Argonaute linker protein Stc1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541372, updated on 18-Sep-2024

    Summary

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    Official Symbol
    stc1
    Official Full Name
    CLRC complex-Argonaute linker protein Stc1
    Primary source
    PomBase:SPBP8B7.28c
    Locus tag
    SPOM_SPBP8B7.28C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See stc1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (3691008..3691915, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ubiquitin-protein ligase E3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene para-aminobenzoate synthase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. CRL4-like Clr4 complex in Schizosaccharomyces pombe depends on an exposed surface of Dos1 for heterochromatin silencing. Kuscu C, et al. Proc Natl Acad Sci U S A, 2014 Feb 4. PMID 24449894, Free PMC Article
    2. Structural analysis of Stc1 provides insights into the coupling of RNAi and chromatin modification. He C, et al. Proc Natl Acad Sci U S A, 2013 May 21. PMID 23613586, Free PMC Article
    3. Raf1 Is a DCAF for the Rik1 DDB1-like protein and has separable roles in siRNA generation and chromatin modification. Buscaino A, et al. PLoS Genet, 2012 Feb. PMID 22319459, Free PMC Article
    4. Ers1 links HP1 to RNAi. Rougemaille M, et al. Proc Natl Acad Sci U S A, 2012 Jul 10. PMID 22733737, Free PMC Article
    5. Elimination of a specific histone H3K14 acetyltransferase complex bypasses the RNAi pathway to regulate pericentric heterochromatin functions. Reddy BD, et al. Genes Dev, 2011 Feb 1. PMID 21289066, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein-macromolecule adaptor activity IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulatory ncRNA-mediated heterochromatin formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in siRNA-mediated pericentric heterochromatin formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in silent mating-type cassette heterochromatin formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in subtelomeric heterochromatin formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in nucleolus HDA PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in pericentric heterochromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    CLRC complex-Argonaute linker protein Stc1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3691008..3691915 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022456.3 → NP_596535.1  CLRC complex-Argonaute linker protein Stc1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596535.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O94276
      Conserved Domains (1) summary
      pfam12898
      Location:42 → 122
      Stc1; Stc1 domain
    Nucleotide Protein
    Heading Accession and Version

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