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    atg44 mitofissin Atg44 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541994, updated on 18-Sep-2024

    Summary

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    Official Symbol
    atg44
    Official Full Name
    mitofissin Atg44
    Primary source
    PomBase:SPAC26A3.14c
    Locus tag
    SPOM_SPAC26A3.14C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    mdi1; SPAC23A6.14c
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    Genomic context

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    See atg44 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003424.3 (3366317..3367125, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene retrotransposable element/transposon Tf2-type Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene nucleoporin Nsp1 Neighboring gene UBA domain protein Dph1/Dsk2 Neighboring gene N-methyltransferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The mitochondrial intermembrane space protein mitofissin drives mitochondrial fission required for mitophagy. Fukuda T, et al. Mol Cell, 2023 Jun 15. PMID 37192628, Free PMC Article
    2. Completion of mitochondrial division requires the intermembrane space protein Mdi1/Atg44. Connor OM, et al. J Cell Biol, 2023 Oct 2. PMID 37540145, Free PMC Article
    3. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
    4. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
    5. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables lipid binding EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables membrane destabilizing activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial fission IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mitochondrial membrane fission EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in mitophagy EXP
    Inferred from Experiment
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm HDA PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in mitochondrial intermembrane space IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitofissin Atg44

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      3366317..3367125 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019581.3 → NP_594157.1  mitofissin Atg44 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594157.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q10167
      Conserved Domains (1) summary
      pfam08520
      Location:4 → 72
      DUF1748; Fungal protein of unknown function (DUF1748)
    Nucleotide Protein
    Heading Accession and Version

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