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    coq8 ABC1 kinase family ubiquinone biosynthesis ATPase Coq8 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540411, updated on 18-Sep-2024

    Summary

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    Official Symbol
    coq8
    Official Full Name
    ABC1 kinase family ubiquinone biosynthesis ATPase Coq8
    Primary source
    PomBase:SPBC2D10.18
    Locus tag
    SPOM_SPBC2D10.18
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    abc1
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    Genomic context

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    See coq8 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (3001174..3003276)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene peptidyl-tRNA hydrolase Pth1 Neighboring gene protein mhf1 Neighboring gene SHREC complex intermodule linker subunit Clr1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ribosome biogenesis protein Alb1 Neighboring gene ubiquitin conjugating enzyme Ubc1 Neighboring gene kinesin-6 family microtubule motor protein Klp9

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The abc1-/coq8- respiratory-deficient mutant of Schizosaccharomyces pombe suffers from glutathione underproduction and hyperaccumulates Cd2+. Gazdag Z, et al. Folia Microbiol (Praha), 2011 Jul. PMID 21818608
    2. Pleiotropic phenotypes of fission yeast defective in ubiquinone-10 production. A study from the abc1Sp (coq8Sp) mutant. Saiki R, et al. Biofactors, 2003. PMID 14695938
    3. Cloning by functional complementation, and inactivation, of the Schizosaccharomyces pombe homologue of the Saccharomyces cerevisiae gene ABC1. Bonnefoy N, et al. Mol Gen Genet, 1996 May 23. PMID 8668131
    4. Polypeptone induces dramatic cell lysis in ura4 deletion mutants of fission yeast. Matsuo Y, et al. PLoS One, 2013. PMID 23555823, Free PMC Article
    5. Functional conservation of coenzyme Q biosynthetic genes among yeasts, plants, and humans. Hayashi K, et al. PLoS One, 2014. PMID 24911838, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The abc1-/coq8- respiratory-deficient mutant of Schizosaccharomyces pombe NBp17 hyperaccumulated yellow CdS.
      Title: The abc1-/coq8- respiratory-deficient mutant of Schizosaccharomyces pombe suffers from glutathione underproduction and hyperaccumulates Cd2+.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables kinase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in ubiquinone biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ubiquinone biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in extrinsic component of mitochondrial inner membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ABC1 kinase family ubiquinone biosynthesis ATPase Coq8

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3001174..3003276
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022157.3 → NP_596237.1  ABC1 kinase family ubiquinone biosynthesis ATPase Coq8 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596237.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q92338
      Conserved Domains (2) summary
      COG0661
      Location:170 → 610
      AarF; Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family [Coenzyme transport and metabolism, Signal transduction mechanisms]
      cd13970
      Location:261 → 511
      ABC1_ADCK3; Activator of bc1 complex (ABC1) kinases, also called aarF domain containing kinase 3
    Nucleotide Protein
    Heading Accession and Version

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