U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    mto1 gamma tubulin complex linker Mto1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539467, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    mto1
    Official Full Name
    gamma tubulin complex linker Mto1
    Primary source
    PomBase:SPCC417.07c
    Locus tag
    SPOM_SPCC417.07C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    mbo1; mod20
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See mto1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_003421.2 (1679761..1683271, complement)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene chitin synthase regulatory factor Neighboring gene ncRNA Neighboring gene protein kinase Mug27/Slk1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Effects of the microtubule nucleator Mto1 on chromosomal movement, DNA repair, and sister chromatid cohesion in fission yeast. Zhurinsky J, et al. Mol Biol Cell, 2019 Oct 1. PMID 31483748, Free PMC Article
    2. Mal3, the Schizosaccharomyces pombe homolog of EB1, is required for karyogamy and for promoting oscillatory nuclear movement during meiosis. Polakova S, et al. Cell Cycle, 2014. PMID 24196444, Free PMC Article
    3. Two distinct regions of Mto1 are required for normal microtubule nucleation and efficient association with the gamma-tubulin complex in vivo. Samejima I, et al. J Cell Sci, 2008 Dec 1. PMID 19001497, Free PMC Article
    4. Interphase microtubule bundles use global cell shape to guide spindle alignment in fission yeast. Daga RR, et al. J Cell Sci, 2008 Jun 15. PMID 18495844
    5. The Dam1/DASH complex is required for the retrieval of unclustered kinetochores in fission yeast. Franco A, et al. J Cell Sci, 2007 Oct 1. PMID 17881496

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables calmodulin binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    contributes_to cytoskeletal protein-membrane anchor activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in astral microtubule nucleation EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in centromere clustering at the mitotic interphase nuclear envelope IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in dynein-driven meiotic oscillatory nuclear movement IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in establishment of mitotic spindle orientation EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in karyogamy involved in conjugation with cellular fusion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in microtubule nucleation by interphase microtubule organizing center IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in nuclear migration by microtubule mediated pushing forces IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in spindle pole body-led chromosome movement during mitotic interphase IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in equatorial microtubule organizing center IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in half bridge of mitotic spindle pole body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in interphase microtubule organizing center IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in microtubule cytoskeleton IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in microtubule organizing center IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in mitotic actomyosin contractile ring, proximal layer EXP
    Inferred from Experiment
    more info
    		 PubMed 
    is_active_in mitotic spindle pole body HDA PubMed 
    is_active_in mitotic spindle pole body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    NOT is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in outer plaque of mitotic spindle pole body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in static microtubule bundle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    gamma tubulin complex linker Mto1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      1679761..1683271 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023274.3 → NP_588284.1  gamma tubulin complex linker Mto1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_588284.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O94488
      Conserved Domains (3) summary
      pfam07989
      Location:252 → 319
      Cnn_1N; Centrosomin N-terminal motif 1
      pfam08702
      Location:511 → 611
      Fib_alpha; Fibrinogen alpha/beta chain family
      pfam12808
      Location:1052 → 1101
      Mto2_bdg; Micro-tubular organizer Mto1 C-term Mto2-binding region
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials