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    cleavage and polyadenylation specificity factor complex subunit [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541907, updated on 18-Sep-2024

    Summary

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    Official Full Name
    cleavage and polyadenylation specificity factor complex subunit
    Primary source
    PomBase:SPAC22H10.05c
    Locus tag
    SPOM_SPAC22H10.05C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (2377677..2380299, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene karyopherin/importin beta family nuclear import signal receptor Kap14 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein phosphatase type 2A Neighboring gene ncRNA Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Post-transcriptional regulation of meiotic genes by a nuclear RNA silencing complex. Egan ED, et al. RNA, 2014 Jun. PMID 24713849, Free PMC Article
    2. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
    3. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article
    4. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360
    5. The mitochondrial genome of the fission yeast Schizosaccharomyces pombe: highly homologous introns are inserted at the same position of the otherwise less conserved cox1 genes in Schizosaccharomyces pombe and Aspergillus nidulans. Lang BF. EMBO J, 1984 Sep. PMID 6092057, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables polynucleotide 5'-hydroxyl-kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway IC
    Inferred by Curator
    more info
    		  
    involved_in tRNA splicing, via endonucleolytic cleavage and ligation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    part_of mRNA cleavage stimulating factor complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    cleavage and polyadenylation specificity factor complex subunit

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      2377677..2380299 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019172.3 → NP_593741.1  cleavage and polyadenylation specificity factor complex subunit [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593741.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q10299
      Conserved Domains (4) summary
      COG5623
      Location:1 → 456
      CLP1; Predicted GTPase subunit of the pre-mRNA cleavage complex [Translation, ribosomal structure and biogenesis]
      pfam06807
      Location:322 → 456
      Clp1; Pre-mRNA cleavage complex II protein Clp1
      pfam16573
      Location:4 → 94
      CLP1_N; N-terminal beta-sandwich domain of polyadenylation factor
      pfam16575
      Location:113 → 315
      CLP1_P; mRNA cleavage and polyadenylation factor CLP1 P-loop
    Nucleotide Protein
    Heading Accession and Version

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