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    SNU56 Snu56p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851827, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SNU56
    Official Full Name
    Snu56p
    Primary source
    SGD:S000002648
    Locus tag
    YDR240C
    See related
    AllianceGenome:SGD:S000002648; FungiDB:YDR240C; VEuPathDB:YDR240C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    MUD10
    Summary
    Enables mRNA binding activity. Involved in mRNA splicing, via spliceosome. Part of U1 snRNP; U2-type prespliceosome; and commitment complex. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See SNU56 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (943674..945152, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene coatomer subunit beta Neighboring gene uncharacterized protein Neighboring gene tRNA-Tyr Neighboring gene putative amidase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Protein arginine methylation of Npl3 promotes splicing of the SUS1 intron harboring non-consensus 5' splice site and branch site. Muddukrishna B, et al. Biochim Biophys Acta Gene Regul Mech, 2017 Jun. PMID 28392442
    2. A single SR-like protein, Npl3, promotes pre-mRNA splicing in budding yeast. Kress TL, et al. Mol Cell, 2008 Dec 5. PMID 19061647, Free PMC Article
    3. Snu56p is required for Mer1p-activated meiotic splicing. Balzer RJ, et al. Mol Cell Biol, 2008 Apr. PMID 18268012, Free PMC Article
    4. Mer1p is a modular splicing factor whose function depends on the conserved U2 snRNP protein Snu17p. Spingola M, et al. Nucleic Acids Res, 2004. PMID 14973223, Free PMC Article
    5. Identification of eight proteins that cross-link to pre-mRNA in the yeast commitment complex. Zhang D, et al. Genes Dev, 1999 Mar 1. PMID 10072386, Free PMC Article

    See all (52) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Snu56p links pre-mRNA-bound Mer1p to Nam8p in the U1 snRNP
      Title: Snu56p is required for Mer1p-activated meiotic splicing.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in RNA splicing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA splicing, via spliceosome IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of U1 snRNP IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of U2-type prespliceosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of commitment complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Snu56p
    NP_010526.1
    • Component of U1 snRNP required for mRNA splicing via spliceosome; yeast specific, no metazoan counterpart; interacts with mRNA in commitment complex

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      943674..945152 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180548.1 → NP_010526.1  TPA: Snu56p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010526.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VSM1, Q03782
      UniProtKB/TrEMBL
      B3LG48, B5VGC7, C7GVB3, C8Z5F1, N1P8G7
      Conserved Domains (1) summary
      pfam19097
      Location:30 → 491
      Snu56_snRNP; Snu56-like U1 small nuclear ribonucleoprotein component
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q03782.1

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