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    YET2 Yet2p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855056, updated on 29-Jun-2024

    Summary

    Gene symbol
    YET2
    Gene description
    Yet2p
    Primary source
    FungiDB:YMR040W
    Locus tag
    YMR040W
    See related
    SGD:S000004643; AllianceGenome:SGD:S000004643; VEuPathDB:YMR040W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport and protein localization to endoplasmic reticulum exit site. Located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in deafness, dystonia, and cerebral hypomyelination and sensorineural hearing loss. Orthologous to human BCAP31 (B cell receptor associated protein 31). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

    See YET2 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (350381..350863)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene copper chaperone CCS1 Neighboring gene chromatin-binding transcription coactivator SUB1 Neighboring gene D-arabinose 1-dehydrogenase (NAD(P)(+)) ARA2 Neighboring gene tRNA-Phe

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein localization to endoplasmic reticulum exit site IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum HDA PubMed 
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Yet2p
    NP_013754.1
    • hypothetical protein that may interact with ribosomes; based on co-purification experiments; homolog of human BAP31 protein; YET2 has a paralog, YET1, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      350381..350863
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182537.1NP_013754.1  TPA: Yet2p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013754.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VZL5, Q04210
      UniProtKB/TrEMBL
      A0A8H4BX92, B3LLT9, C7GL79, C8ZEP7, N1P074
      Conserved Domains (1) summary
      cl02219
      Location:1160
      Bap31; B-cell receptor-associated protein 31-like