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    Fbxw17 F-box and WD-40 domain protein 17 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361219, updated on 10-Jul-2024

    Summary

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    Official Symbol
    Fbxw17provided by RGD
    Official Full Name
    F-box and WD-40 domain protein 17provided by RGD
    Primary source
    RGD:1566133
    See related
    EnsemblRapid:ENSRNOG00000030027 AllianceGenome:RGD:1566133
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1566133
    Expression
    Biased expression in Lung (RPKM 39.2), Kidney (RPKM 36.7) and 9 other tissues See more
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    Genomic context

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    See Fbxw17 in Genome Data Viewer
    Location:
    17p14
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (14511173..14529021)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (14359533..14379386)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (15076773..15094635, complement)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene spermatogenesis-associated protein 31E1-like Neighboring gene SPATA31 subfamily A member 5 like 1 Neighboring gene hypothetical protein LOC689316 Neighboring gene NUT family member 2 Neighboring gene uncharacterized LOC134482691 Neighboring gene SPATA31 subfamily C member 2 like 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    Fbxw17 protein; fbxw17 protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001082409.1 → NP_001075878.1  Fbxw17 protein

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/TrEMBL
      D3Z9G1
      Related
      ENSRNOP00000039789.5, ENSRNOT00000044073.6
      Conserved Domains (4) summary
      COG2319
      Location:90 → 417
      WD40; WD40 repeat [General function prediction only]
      pfam12937
      Location:7 → 48
      F-box-like; F-box-like
      sd00039
      Location:151 → 186
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:90 → 408
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      14511173..14529021
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008771541.4 → XP_008769763.3  fbxw17 protein isoform X1

    2. XM_039095862.2 → XP_038951790.2  fbxw17 protein isoform X6

    3. XM_063276563.1 → XP_063132633.1  fbxw17 protein isoform X5

    4. XM_063276561.1 → XP_063132631.1  fbxw17 protein isoform X3

      UniProtKB/TrEMBL
      A6J6U9

    5. XM_063276562.1 → XP_063132632.1  fbxw17 protein isoform X4

    6. XM_039095860.2 → XP_038951788.1  fbxw17 protein isoform X2

      UniProtKB/TrEMBL
      D3Z9G1
      Conserved Domains (2) summary
      COG2319
      Location:65 → 392
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:126 → 161
      7WD40; WD40 repeat [structural motif]

    7. XM_063276564.1 → XP_063132634.1  fbxw17 protein isoform X5

    8. XM_063276565.1 → XP_063132635.1  fbxw17 protein isoform X5

    9. XM_039095861.2 → XP_038951789.1  fbxw17 protein isoform X5

    Nucleotide Protein Strain
    Heading Accession and Version

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