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    F59A2.5 ACT domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 175444, updated on 18-Sep-2024

    Summary

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    Official Symbol
    F59A2.5
    Official Full Name
    ACT domain-containing protein
    Primary source
    WormBase:WBGene00010305
    Locus tag
    CELE_F59A2.5
    See related
    AllianceGenome:WB:WBGene00010305
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in tRNA threonylcarbamoyladenosine metabolic process. Predicted to be part of EKC/KEOPS complex. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome 2. Orthologous to human LAGE3 (L antigen family member 3). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See F59A2.5 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    3
    Sequence:
    Chromosome: III; NC_003281.10 (3404863..3405469)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Pre-mRNA cleavage complex subunit Clp1 C-terminal domain-containing protein;Protein clpf-1 Neighboring gene Nuclear Pore complex Protein Neighboring gene GRIP domain-containing protein Neighboring gene ncRNA Neighboring gene protein-histidine N-methyltransferase Neighboring gene tRNA-Lys Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression. Reboul J, et al. Nat Genet, 2003 May. PMID 12679813
    2. A global analysis of genetic interactions in Caenorhabditis elegans. Byrne AB, et al. J Biol, 2007. PMID 17897480, Free PMC Article
    3. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in tRNA threonylcarbamoyladenosine metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of EKC/KEOPS complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    ACT domain-containing protein
    NP_497704.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      3404863..3405469
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_065303.4 → NP_497704.1  ACT domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497704.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q21019
      Conserved Domains (1) summary
      pfam09341
      Location:28 → 100
      Pcc1; Transcription factor Pcc1
    Nucleotide Protein
    Heading Accession and Version

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