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    T28C12.1 Major facilitator superfamily (MFS) profile domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 189037, updated on 12-Jun-2024

    Summary

    Gene symbol
    T28C12.1
    Gene description
    Major facilitator superfamily (MFS) profile domain-containing protein
    Locus tag
    CELE_T28C12.1
    See related
    AllianceGenome:WB:WBGene00020888
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 7. Orthologous to human MFSD8 (major facilitator superfamily domain containing 8). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

    See T28C12.1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    7
    Sequence:
    Chromosome: V; NC_003283.11 (6331907..6334037)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene F-box domain-containing protein Neighboring gene Major facilitator superfamily (MFS) profile domain-containing protein Neighboring gene WAP domain-containing protein Neighboring gene tRNA-Cys Neighboring gene ncRNA

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in lysosomal membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Major facilitator superfamily (MFS) profile domain-containing protein
    NP_504617.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      6331907..6334037
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_072216.4NP_504617.2  Major facilitator superfamily (MFS) profile domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504617.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      O16698
      Conserved Domains (1) summary
      cd17326
      Location:21458
      MFS_MFSD8; Major facilitator superfamily domain-containing protein 8